Formulations for delivery of osteogenic proteins

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai

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Details

530350, 530397, 530399, 530840, 514 8, 514 21, 424423, 424426, 106645, A61K 3702, C07K 1300

Patent

active

053858875

ABSTRACT:
A composition is disclosed comprising a pharmaceutically acceptable admixture of an osteogenic protein; a porous particulate polymer matrix; an osteogenic protein-sequestering amount of blood clot; and a calcium sulfate hemihydrate-containing substance. Also disclosed are formulations of bone morphogenetic proteins with improved solubility and/or stability characteristics.

REFERENCES:
patent: 5013649 (1991-05-01), Wang et al.
patent: 5171579 (1992-12-01), Ron et al.

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