Formulations containing coumarins and the use thereof in the pha

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Cosmetic – antiperspirant – dentifrice

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4241951, 424 59, 424 60, A61K 3135, A61K 3170

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active

056653654

ABSTRACT:
The present invention relates to the use of coumarins such as esculoside, esculetin, extracts containing them and mixtures thereof, in combination with dimeric and oligomeric proanthocyanidins, in topical formulations for the treatment of peripheral vasculopathies, including the complications of acute venous stasis, or of the unesthetisms related to capillary alterations, or to improve the cicatrization processes. These coumarins, alone or in combination with proanthocyanidins, are also useful in atopical dermatitis and in the treatment of the haematomas.

REFERENCES:
patent: 4925871 (1990-05-01), Gabetta et al.
patent: 4963527 (1990-10-01), Bombardelli et al.
Phlebologie (Germany), 1944, "Hostettmann K. et al. Zu 'Inhaltsstoffen und Pharmakologie Pflanzicher Venemittel"; p. 72, col. 1, para. 3 --p. 73, col. 3, para. 2.

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