Formulations and methods of reducing toxicity of antineoplastic

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Cyclopentanohydrophenanthrene ring system doai

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514182, 514284, 514328, 514365, 514453, 514555, 514626, 514648, 514733, 514772, 514946, 514947, A61K 3822

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060488492

ABSTRACT:
This invention provides for pharmaceutical formulations of compounds which are useful as protective agents when administered to patients also receiving antineoplastic drugs. The invention also includes methods of reducing the toxicity of various antineoplastic agents by administering an effective amount of the protective agent to a patient receiving one or more antineoplastic agents. The compounds useful as protective agents have either a sulfhydryl moiety or are reducible disulfides.

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