Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1997-10-17
1999-07-06
Raymond, Richard L.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514 83, 514100, 514108, 514110, 514127, 514128, 514138, 514221, 514241, 514258, 514260, 514266, 514274, 514283, 514348, 514398, 514413, 514456, 514460, 514492, 514517, 514567, 514578, 514590, 514615, 514649, 514672, 514748, A61K 31335
Patent
active
059198168
ABSTRACT:
This invention provides for pharmaceutical formulations of compounds which are useful as protective agents when administered to patients also receiving antineoplastic drugs. The invention also includes methods of reducing the toxicity of various antineoplastic agents by administering an effective amount of the protective agent to a patient receiving one or more antineoplastic agents. The compounds useful as protective agents have either a sulfhydryl moiety or are reducible disulfides.
REFERENCES:
patent: 4310515 (1982-01-01), Granatek et al.
PDR Physicians' Desk Reference, 48 Edition 1994, Medical Consultant Ronald Arky, MD, p. 661.
Dodd Thomas J.
Hausheer Frederick H.
BioNumerik Pharmaceuticals, Inc.
Dodd Thomas J.
Raymond Richard L.
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