Formulations and methods for reducing skin irritation

Details Formulations and methods for reducing skin irritation Formulations and methods for reducing skin irritation

1994-12-21

1998-05-26

Gardner, Sallie M.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Cosmetic, antiperspirant, dentifrice

424 59, 424 65, 424 701, 424 73, 4241951, 424677, 424722, 424436, 424430, 424 49, 424402, 424447, 514846, 514847, 514848, 514859, A61K 700, A61K 706

Patent

active

057561079

ABSTRACT:
Topical formulations comprising an anti-irritant amount of aqueous-soluble lithium (Li.sup.+) or potassium (K.sup.+) cation, and methods for using the same to inhibit skin irritation, are disclosed.

REFERENCES:
patent: 4105782 (1978-08-01), Yu et al.
patent: 4105783 (1978-08-01), Yu et al.
patent: 4191750 (1980-03-01), Hodosh
patent: 4285973 (1981-08-01), Edwards
patent: 4388301 (1983-06-01), Klein
patent: 4447439 (1984-05-01), D'Alelio
patent: 4943432 (1990-07-01), Biener
patent: 4971800 (1990-11-01), Chess et al.
patent: 5079010 (1992-01-01), Natterer
patent: 5262153 (1993-11-01), Mishima et al.
Abel, Elizabeth A., "Phototherapy", Dermatologic Clinics, 13(4):841-849, Oct. 1995.
Arky, Ronald, et al. (Eds.), Physicians Desk Reference, 49th Edition, 1995, p. 929.
Bayless, J. Mark, et al., "Diagnosis and Treatment of Acute Fluoride Toxicity", Am. Dental Ass'n., 110:209-211, Feb. 1985.
Bilotto, Gerardo, et al., "Effects of Ionic and Non-Ionic Solutions on Intradental Nerve Activity in the Cat," Pain, 32: 231-238, 1988.
Budavari, Susan, et al. (Eds.), The Merck Index, (Merck & Co., Inc., 1989), pp. 708, 1218.
Degroot, Unwanted Effects of Cosmetics and Drugs Used in Dermatology, 1995, p. 229.
Drug Facts and Comparisons, 1995 Edition (Facts and Comparisons, St. Louis, MO), pp. 37-38.
Fitzpatrick, Thomas B., et al. (Eds.), Dermatology In General Medicine, (McGraw-Hill, Inc. 1993), 4th Ed., vol. 1, pp. 501, 508-510.
Gilman, Alfred Goodman et al., The Pharmacological Basis of Therapeutics, (McGraw-Hill, Inc. 1993), pp. 1291, 1581, 1586.
Gonzalez, Ernesto, "PUVA for Psoriasis", Dermatologic Clinics, 13(4):851-866, Oct. 1995.
Greaves, Malcolm W., et al., "Treatment of Psoriasis," New Engl. J. Med., 332(9): 581-588, Mar. 1995.
Griffiths, Tamara W. et al., "Immunopathogenesis and Immunotherapy of Psoriasis", Dermatologic Clinics, 13(4):739-749, Oct. 1995.
Hallmans, Goran, "Local Absorption of Zinc from Wounds Treated with Different Concentrations of Zinc Sulphate", Acta Dermatovener (Stockholm), 58:413-419, 1978.
Jeffes III, Edward W.B., et al., "Methotrexate and Other Chemotherapeutic Agents Use to Treat Psoriasis", Dermatologic Clinics, 13(4): 875-890, Oct. 1995.
Katz, H. Irving, "Topical Corticosteroids", Dermatologic Clinics, 13(4):805-815, Oct. 1995.
Kim, Syngcuk, "Hypersensitive Teeth: Desensitization of Pulpal Sensory Nerves," J. Endodontics, 12(10): 482-485, Oct. 1986.
Koo, John et al., "Cyclosporine: What Clinicians Need to Know", Dermatologic Clinics, 13(4):897-907, Oct. 1995.
Kragballe, Knud, "Vitamin D.sub.3 Analogues", Dermatologic Clinics, 13(4):835-839, Oct. 1995.
Lansdown, A.B.G., "Interspecies Variations in Response to Topical Application of Selected Zinc Compounds", Food Chem. Toxic., 29(1):57-64, 1991.
Lebwohl, Mark, "Future Psoriasis Therapy", Dermatologic Clinics, 13(4):915-923, Oct. 1995.
Lowe, Nicholas J., et al., "Generalized Pustular Psoriasis Precipitated by Lithium Carbonate," Arch. Dermatol., 114: 1788-1789, Dec. 1978.
Markowitz, K., et al., "Decreasing Intradental Nerve Activity in the Cat with Potassium and Divalent Cations," Archs. Oral Biol., 36(1): 1-7, 1991.
Markowitz, Kenneth, et al., "The Role of Selected Cations in the Desensitization of Intradental Nerves," Proc. Finn. Dent. Soc., 88 (Suppl I): 39-54, 1992.
Momtaz-T., Khosrow, "Modifications of PUVA", Dermatologic Clinics, 13(4):867-873, Oct. 1995.
Morris, Christopher J. et al., "Reactive Oxygen Species and Iron--a Dangerous Partnership in Inflammation", Int. J. Biochem. Cell Biol., 27(2):109-122, 1995.
Salvato, Anthony R., et al., "Clinical Effectiveness of a Dentrifice Containing Potassium Chloride as a Desensitizing Agent," Am. J. Dent., 5(6): 303-306, Dec. 1992.
Serup, Jorgen et al., "Epidermal Hydration of Psoriasis Plaques and the Relation to Scaling: Measurement of Electrical Conductance and Transepidermal Water Loss", Acta Derm Venereol (Stockholm), 67:357-359, 1987.
Silverman, A.K., et al., "Tars and Anthralins," Dermatologic Clinics, 13(4): 816-834, Oct. 1995.
Tagami, Hachiro et al., "Interrelationship Between Water-Barrier and Reservoir Functions of Pathologic Stratum Corneum", Arch. Dermatol., 121:642-645, May 1985.
Wieder, Joshua M. et al., "Systemic Retinoids for Psoriasis", Dermatologic Clinics, 13(4):891-896, Oct. 1995.
Wilkinson, J.B., et al. (Eds.), Harry's Cosmeticology (Chemical Publishing Company, New York, New York, 1982), p. 74.

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