Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Nitrogen containing other than solely as a nitrogen in an...
Patent
1985-07-11
1987-02-24
Moyer, Donald B.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Nitrogen containing other than solely as a nitrogen in an...
564367, A61K 31330, C07C 8728
Patent
active
046457682
ABSTRACT:
There is described a mixture of 4-[2-(6-(2-phenylethylamino)hexylamino)ethyl]-1,2-benzenediol, or 4-[2-(6-(2-chlorophenyl)ethylamino)hexylamino)ethyl]-1,2-benzenediol or a pharmaceutically acceptable acid addition salt of either thereof or as active ingredient, and a physiologically acceptable acid.
There is also described a method of preparing a solid form of the active ingredient, which comprises freeze drying an aqueous solution of the mixture, and a freeze dried composition containing the active ingredient prepared by the method.
The mixtures are useful as pharmaceuticals, e.g. in the treatment of cardiovascular conditions.
REFERENCES:
patent: 2653977 (1953-09-01), Craig et al.
patent: 3969410 (1976-07-01), Mentrup et al.
patent: 4010282 (1977-03-01), Binnig et al.
"Remington's Phar. Sciences" 16th Ed., pp. 1432-1433 and 1483-1484 (1980).
Fisons plc
Moyer Donald B.
Rollins Jr. John W.
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