Formulation useful as a natural herbal tooth powder

Drug – bio-affecting and body treating compositions – Dentifrices – Plant extract of undetermined constitution

Reexamination Certificate

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C424S195110, C424S049000

Reexamination Certificate

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06264926

ABSTRACT:

FIELD OF INVENTION
This invention relates to the development of a formulation useful as a herbal tooth powder for gums and teeth. More particularly, the invention provides a formulation useful for the treatment of pyorrhoea, yellowing/staining of teeth and sensitivity of teeth to hot/cold water and food.
BACKGROUND OF INVENTION
The main diseases of the teeth include plaque, caries and pyorrhoea. Proper dental care is necessary for eliminating tooth decay and periodental diseases. The people living in Indian subcontinent largely depend on the traditional systems for the treatment of toothache, caries and other diseases related to teeth. The traditional herbal preparations for dental care comprise of various types of herbal powders and chewing sticks made out of young woody stem or root pieces. The table-1 gives a list of plants which are used for oral health by the people of India. It is compiled from the literature reports (Almass K., Al-Lafi, Tr., World Health Forum 16:206-210, 1995; Chopra et al., Glossary of Indian Medicinal Plants, 1956; Manandhar N P, J. Econ. Tax. Bot., 12:408-413, 1997; Rao et al. Ethnobot., 8:88-91, 1996; Rispler-Chaim V, J Royl Asiatic Soc. V2:13-20, 1992 and Sushil Kumar et al. Medicinal Plants in Skin Care, CIMAP, 76-89, 1994).
TABLE 1
The plants that are employed for tooth care in India
S1.
No.
Botanical and Indian common names
Purpose and method of use
 1.
Acacia catechu
Catechu paste is used to treat the bleeding
(Katha)
gums and for tooth hypersensitivity.
 2.
A. nilotica
Fresh twig is used as tooth brush for keeping
(Kikar)
the gums and teeth healthy and clean.
 3.
Achyrathes aspera
Twing is used for brushing teeth.
(Puthkanda, Latjira)
to treat dental problems
 4.
Azadirachta indica
Fresh twig is used as tooth
(Neem)
brush to prevent gum diseases
and pyorrhoea
 5.
Aristolochia bracteolata
Root juice is applied to the site
(Kidamari)
of toothache for relieving pain
 6.
Cinnamomum camphora
Tender twigs are chewed or the paste of
(Kapur)
stem bark is applied in aching teeth
 7.
Cinnamomum verum
Powdered stem bark is applied to
(Dalchini)
teeth in the treatment of caries
and pyorrhoea
 8.
Curcuma longa
Powder of rhizome is used in tooth
(Turmeric)
powder for curing pyorrhoea
 9.
Eucalyptus globulus
To prevent tooth decay and
(Karpoora)
to provide relief form pain
the leaf oil is applied to
the site of pain
10.
Ficus bengalensis
Aerial root is used as
(Bargad)
tooth brush and the latex is
applied in toothache
11.
Juglans regia
Stem bark is used in tooth
(Akhrot)
powders to make the teeth
healthy
12.
Madhuca longifolia
Stem bark is used in tooth
(Mahua)
powder for gum pain and
toothache
13.
Mimusops elengi
Bark is used in tooth
(Maulsari)
powder for the protection
of gums and teeth
14.
Myristica fragrans
Fruit paste is applied on
(Jaiphal)
teeth to cure dental caries
and pyorrhoea
15.
Ocimum sanctum
Leaves are chewed as such for
(Tulsi)
the treatment of bad breath
and leaf paste is usefull
for tooth hypersensitivity
16.
Piper betel
Leaf paste is suggested for
(Pan)
dentinal hypersensitivity
17.
Piper longum
Fruit in the form of powder
(Piplamus)
is applied for dental caries
18.
Piper nigrum
Fine powder of seeds is applied
(Goal mirch)
to teeth in toothache, pyorrhoea
and gum bleeding
19.
Potentilla fulgens
Root powder is applied
(Vajardanti)
in gingivitis
20.
Punica granatum
Stem bark or fruits rind is used
(Anar)
as component of dental powder
21.
Salvadora persica
Twig is used as tooth brush
(Pilu)
for cleaning the teeth.
Roots are used in dental caries,
and to relieve toothache
22.
Syzygium aromaticum
Clove oil is applied for
(Laung)
toothache, dental
caries and pyorrhoea
23.
Spilanthes calva
Flowers chewed in toothache.
(Akarkara)
Plant made into paste is applied
in toothache
24.
Zanthoxylum armatum
Twig is used as tooth brush
(Tejbal)
for cleaning the teeth.
Fruit powder is applied
to teeth in toothache.
In the Indian subcontinent the commonest source of chewing sticks is
Azadirachta indica. Salvador persica
stems and roots are also widely used as chewing sticks. Chewing sticks obtained from
A. indica
contain essential oils and exert carminative, antiseptic and analgesic action. The tannins of chewing sticks have an astringent effect on mucous membrane.
Many plants are useful in pyorrhoea.
Cinnamomum verum
bark is an astringent and is thus useful for checking the bleeding of gums. The bark has essential oil and tannins. The essential oil of
C. verum
has antimicrobial and antibacterial properties.
Accacia nilotica
bark and ash of almond kernel can be pulverized together and mixed with common salt to make a highly effective preparation to contain pyorrhoea and for strengthening of gums by making them strong. Use of clove oil is recommended for the alleviation of toothache.
At present, a number of tooth powders are available in India which contain cheap pulverized items that are not very effective as well as harmful for gums and teeth and have toxic effects. Composition of some of the herbal tooth powder available in market are given below.
Manufacturer and
S.No.
Product name
address
Ingredients
1.
Red Tooth Powder
Dabur India Ltd.
Pudina satva (Mentha sp.),
22, Site IV Sahibabd,
lavang ka tail (
Syzygium
Ghaziabad
aromaticum
), Tomer beej
(
Zanthoxylum acanthopodium
),
Kapoor, Kalimarich (
Piper
nigrum
), Pippali (
Piper
longum
), Sunthi (
Zingiber
officinale
), Tambaku
(
Nicotiana tabacum
)
2.
Vicco Vajradanti
Vicco Laboratories
Babbul (
Acacia nilotica
),
25, Jerbi Wadia Road,
Janibhul, Lavang (
Syzygium
Parel,Bombay-400012
aromaticum
), Manjishtha
(
Rubia cordifolia
), Dalchini
(
Cinnamomum zeylanicum
),
Vajradanti (
Potentilla
fulgens
), Acrod, Khair
patang, Akkal Kadha, Babul,
Jeshthamadh, Kabachini
(
Piper cubaba
), Anant root
(
Hemidesmus indicus
),Ajwain
(
Trachyspernum ammi
), Jaifal
(
Myristica fragrans
),
Trifala (
Emblica officinals
,
Terminalia chabula
,
Terminalia belerica
), rice
husk, sugar, alum, salt.
3.
Lordent
Lord's Cosmetics
Extract of Plantago,
Toothpowder
International
Calendula and creosote
A-21/27, Naraina
Industrial Area,
Phase-II
New Delhi-110028
4.
Meghdoot dantusha
Meghdoot Gramodhyog
Sonth (
Zingiber officinale
),
Seva Sansthan,
Pipal (
Ficus religiosa
),
Meghdoot Buliding
Kalimirch (
Piper nigrum
),
Chandganj Garden,
Tomar beej (
Zanthoxylum
Lucknow
acanthopodium
), Samundar
Jhag, Akarkara (
Anacyclus
pyrethrum
) Manjuphal,
Maulshri (
Mimosops elengi
),
Sengdha salt.
5.
Payorin
Dawakhana Tibbiya
Amla (
Emblica officinalis
)
College, AMU, Alighrh
Sokhta, Gile gaimuliya, Taj
galmi, Kafoor khlis, Hamize
fahmi, Roghan Asfaidar
6.
Hamdard Manjan
Hamdard (Wakf)
Ilaichi (
Electtaria cardamo
-
Laboratories
mum
) kalan, Amla (
Emblica
Hamdard Marg,
officinalis
) dry, Post
Delhi-110 006
halaila zard (
Terminalia
chebula
), Banslochan
(
Bambusa bambos
), Zanjbeel
(
Zingiber officinale
),
Sangjarahat, Filfil siyah
(
Piper nigrum
), Kabab
khandan, Khoolanjan (
Alpinia
galanga
), Namak Sambhar,
Mileh firangi, Sat paudina
(Mentha spp)
7.
MDH Dant powder
Super Delicocies
i)
Acacia nilotica
Pvt. Ltd.
ii)
Embelia tsjenam-cottam
iii)
Areca catechu
iv)
Juglans regia
v)
Curcuma amada
vii)
Syzygium aromaticum
viii)
Alpinia galanga
Ficus elastica
,
Piper nigrum
Menthol, Eucalyptus_oil.
8.
Payakil
Gurukul Pharmacy
Acacia nilotica
Hardwar
Suglans regia
,
Camphora
officinatum
,
Azadirachta
indica
,
Arcila vitrolutcum,
Zanthoxylum armatum,
Zanthoxylum armatum.
The above described formulations suffer from a number of disadvantages.
1. Some formulations have harmful components e.g.
Nicotiana tabacum
which ultimately spoil the teeth and gum.
2. Adulteration of plant material is often there. Therefore, the formulations have not been found very effective.
3. The product very often have cheap materials and expansive items are not used in the prescribed quantity. Therefore, the final product is not very useful.
4. Very often the amount of base material is more compared to active components and thus the product is not very useful.
OBJECTS OF THE INVENTION
The main object of the

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