Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...
Reexamination Certificate
2007-06-05
2007-06-05
Wax, Robert A. (Department: 1656)
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Recombinant dna technique included in method of making a...
C530S416000, C530S412000
Reexamination Certificate
active
11337518
ABSTRACT:
Compositions are described that are suitable for formulating TFPI. Solubilizers and stabilizers facilitate the preparation of pharmaceutically acceptable compositions of TFPI at various concentrations.
REFERENCES:
patent: 4637834 (1987-01-01), Thurow
patent: 5051497 (1991-09-01), Fanning et al.
patent: 5212091 (1993-05-01), Diaz-Collier et al.
patent: 5276015 (1994-01-01), Khouri et al.
patent: 5358708 (1994-10-01), Patel
patent: 5466783 (1995-11-01), Wun et al.
patent: 5503827 (1996-04-01), Woog et al.
patent: 6103500 (2000-08-01), Innis et al.
patent: 6323326 (2001-11-01), Dorin et al.
patent: 2005/0037475 (2005-02-01), Reifsnyder et al.
patent: 0473 564 (1992-03-01), None
patent: 0 559 632 (1993-09-01), None
patent: WO 93/25230 (1993-12-01), None
patent: WO 96/01649 (1996-01-01), None
Rainer Rudolph, “Successful Protein Folding on an Industrial Scale”, Protein Engineering: Principles and Practice, Chapter 10, pp. 283-298, dated 1996.
Rudolph & Lillie, “In vitro folding of inclusion body proteins”, Folding of Acidic Fibroblast Growth Factor, FASEB J., 10, pp. 49-56.
Dabora et al., “Effect of Polyanions on the Refolding of Human Acidic Fibroblast Growth Factor”, The Journal of Biological Chemistry, vol. 266, No. 35, pp. 23637-23640, dated Dec. 15, 1991.
Bernhard Fisher et al., “Isolation, Renaturation, and Formation of Disulfide Bonds of Eukaryotic Proteins Expressed inEscherichia colias Inclusion Bodies”, Biotechnology and Bioengineering, vol. 41, pp. 3-13, dated 1993.
J. Harenberg, et al., “Tissue factor pathway inhibotor: proposed heparin recognition region”, Blood Coagulation and Fibrinolysis, vol. 6, Supp. No. 1, pp. S50-S56, dated 1995.
Mark E. Gustafson et al., “Renaturation and Purification of Human Tissue Factor Pathway Inhibitor Expressed in RecombinantE. coli, Protein Expression and Purification”, vol. 5, pp. 233-241, dated 1994.
Arve Bo H.
Bild Gary S.
Chen Bao-Lu
Dorin Glenn J.
Gustafson Mark E.
G.D. Searle LLC
Novartis Vaccines and Diagnostics Inc.
Wax Robert A.
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