Chemistry: analytical and immunological testing – Including sample preparation – Volumetric liquid transfer
Patent
1995-05-23
1996-12-10
Warden, Jill
Chemistry: analytical and immunological testing
Including sample preparation
Volumetric liquid transfer
422103, G01N 110
Patent
active
055830528
ABSTRACT:
A formulation preparation device is provided herein which contains a valve assembly, transfer spikes, syringe port and tube, these components being interconnected so as to provide for controlled fluid flow between the spikes and port, through the assembly, in specific directions only. The device has an enclosed, sterilizable, gripable housing and can be used to mix combine fluids in reproducible and predetermined proportions. Combination is accomplished aseptically, avoiding contact between the device's operator and the fluids and the substances combined. Biologically active compounds can be combined with one or more fluids, including such aqueous liposome suspensions, using the device. A formulation preparation kit containing, in addition to the device, the fluids and compounds to be formulated is thus also provided herein; methods of using the device to prepare such formulations are further provided herein.
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Bartholomew Joel
Coe Royden M.
Grimm John
Portnoff Joel B.
Raines Kenneth
B. Braun Medical Inc.
Markoff Alexander
Rubin Kenneth B.
The Liposome Company Inc.
Warden Jill
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