Formulation of and dehydration of hydroxylated diphenyl acetylen

Organic compounds -- part of the class 532-570 series – Organic compounds – Oxygen containing

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568716, 568731, 568743, 568744, 568745, C07C 3700, C07C 3921

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054203619

ABSTRACT:
The production of cis-dihydrodiol compounds of the formula ##STR1## where n is 0 or 1 (preferably 0) by the microbial oxidation of a diphenylaceylene compound of the formula ##STR2## using a mutant of a Pseudomonas bacteria at 25.degree. to 35.degree. C. and pH 6-8 is disclosed. The cis-dihydrodiol compound is in turn treated with an aqueous solution of a base to produce a corresponding 3-hydroxydiphenylacetylene compound or with an aqueous solution of an acid to produce a corresponding 2-hydroxyacetylene compound.

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