Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving transferase
Patent
1992-09-14
1994-03-29
Wax, Robert A.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving transferase
435188, 435194, C12Q 150, C12N 996, C12N 912
Patent
active
052984060
ABSTRACT:
A formulation for stabilizing enzymatic activity and immunoreactivity of creatine kinase and creatine kinase isoenzymes comprising animal serum, creatine kinase and/or creatine kinase isoenzymes, an effective amount of a buffer having a pKa in the range of 6.2-7.6 to maintain pH of the formulation at 6.7.+-.0.1, an effective amount of a non-thiol antioxidant to prevent oxidation of creatine kinase or creatine kinase isoenzyme thiol groups, an effective amount of a non-reducing polyol to stabilize immunoreactivity of creatine kinase or creatine kinase isoenzymes, and an effective amount of an antimicrobial to prevent microbial growth is provided.
REFERENCES:
patent: 4276376 (1981-06-01), Hundt et al.
patent: 4442212 (1984-04-01), Briggs
patent: 4931392 (1990-06-01), Rehner et al.
patent: 4994375 (1991-02-01), Posner et al.
Halliwell, B. et al. "The Antioxidants of Human Extracellular Fluids." Arch. Biochem. Biophys. 280(1) 1-8 (Jul. 1990).
Clin Biochem, vol. 25, pp. 11-13, 1992 Joseph E. Buttery, et al.
Loyd Joseph E.
Search Barbara A.
E. I. Du Pont de Nemours and Company
Prouty Rebecca
Wax Robert A.
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