Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Particulate form
Reexamination Certificate
2007-10-09
2007-10-09
Kishore, Gollamudi S. (Department: 1615)
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Particulate form
C424S043000, C424S044000, C424S046000, C424S502000
Reexamination Certificate
active
10833613
ABSTRACT:
Particles having a tap density less than about 0.4 g/cm3 are formed by spray drying from a colloidal solution including a carboxylic acid or salt thereof, a phospholipid, a divalent salt and a solvent such as an aqueous-organic solvent. The colloidal solution can also include a therapeutic, prophylactic or diagnostic agent. Preferred carboxylic acids include at least two carboxyl groups. Preferred phospholipids include phosphatidylcholines, phosphatidylethanolamines, phosphatidylglycerols, phophstidylserines, phosphatidylinositols and combinations thereof. The particles are suitable for pulmonary delivery.
REFERENCES:
patent: 5855913 (1999-01-01), Hanes et al.
patent: 5997848 (1999-12-01), Patton et al.
patent: 6315983 (2001-11-01), Eistetter
Batycky Richard P.
Caponetti Giovanni
Lipp Michael W.
Advanced Inhalation Research, Inc.
Elmore Carolyn S.
Elmore Patent Law Group, PC.
Kishore Gollamudi S.
Vanstone Darlene A.
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