Formulation for delivery of drugs by metered dose inhalers with

Surgery – Liquid medicament atomizer or sprayer

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Details

12820023, 12820315, 12820323, 222635, 252305, 424 45, 424 46, A61K 912, A61M 1100, C09K 330

Patent

active

051900297

ABSTRACT:
Aerosol formulations for use in metered dose inhalers are disclosed which include 1,1,1,2-tetrafluoroethane alone and in combination with other compounds as well as various hydrocarbon blends. The density, vapor pressure, flame extension characteristics, dispersability of medicant, dissolvability of surfactant, respirable fraction, and compatibility elastomer seals for the aerosol formulations have been examined. The aerosol formulations are attractive alternatives to chlorofluorocarbon based aerosols since they do not deplete the ozone layer.

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Nelson et al.: "Alternative Formulation to Reduce CFC Use in U.S. Exempted and Excluded Aerosol Products", EPA-600/2-89-061, Nov. 1989.
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