Formulation comprising antibacterial substance and antiulcer sub

Details Formulation comprising antibacterial substance and antiulcer sub Formulation comprising antibacterial substance and antiulcer sub

1997-05-27

1999-09-07

Goldberg, Jerome D.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

514338, A61K 3143, A61K 3444

Patent

active

059487739

ABSTRACT:
The present invention includes a formulation which comprises an antibacterial substance and an antiulcer substance, wherein at least either of them is formulated into a gastrointestinal mucosa-adherent solid preparation. The formulation of the present invention shows long retention time in the gastrointestinal tract because of adhesion to the gastrointestinal tract mucosa, synergetically enhances the pharmaceutical effects of an antibacterial substance, specially antibiotic against Helicobacter pylori (HP) and an antiulcer substance, with very low doses of active ingredients, particularly the anti-HP antibiotic with low prevalence of side effects. The present agent is useful as an anti ulcer agent, showing potent anti-HP activity.

REFERENCES:
patent: 4912093 (1990-03-01), Michaeli
patent: 5045321 (1991-09-01), Makino et al.
P. Unge et al., "Does Omeprazole Improve Antimicrobial Therapy Directed Towards Gastric Campylobacter Pylori in Patients with Antral Gastritis?", Scandinavian Journal of Gastroenterology, vol. 24, Supplement 167, 1989, pp. 49-54.
T. Shimoyama et al., Is it an Exaggeration to Say "No Helicobacter pylori, no ulcer?", Peptic Ulcer Review--Current Topics, Oct. 1992, with English translation.

Affiliated with

Also associated with

Rating

Formulation comprising antibacterial substance and antiulcer sub does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Formulation comprising antibacterial substance and antiulcer sub, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Formulation comprising antibacterial substance and antiulcer sub will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1804638