Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Radical -xh acid – or anhydride – acid halide or salt thereof...
Patent
1994-10-04
1996-10-01
Henley, III, Raymond
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Radical -xh acid, or anhydride, acid halide or salt thereof...
A61K 3119
Patent
active
055611605
ABSTRACT:
The present invention provides a formula and method for the prevention and treatment of hypercholesterolemia and cellular hyperproliferation. More specifically, the present invention provides a method for administering a formula including glucaric acid or a pharmaceutically acceptable salt thereof for the prevention and treatment of hypercholesterolemia and cellular hyperproliferation in humans and animals. It has been determined that glucaric acid and pharmaceutically acceptable salts thereof significantly lower the total and LDL level of serum cholesterol and inhibit cellular hyperproliferation when administered in therapeutic amounts. It is intended that glucaric acid or a pharmaceutically acceptable salt thereof is employed alone or in combination with other medicinal agents for the prevention and treatment of hypercholesterolemia and cellular hyperproliferation.
REFERENCES:
patent: 3697287 (1972-10-01), Winitz
patent: 4751085 (1988-06-01), Gaull
patent: 4845123 (1989-07-01), Walaszek et al.
patent: 5364644 (1994-11-01), Walaszek et al.
Berkon et al., "The Merck Manual", published 1982 by Merck Sharp & Dohme Research Labs (N.J.) see pp. 970-977.
Garrison et al. "The Nutrition Desk Reference" published 1985 by Keats Publishing Inc., (Conn) see pp. 172-180.
Hanauek Margaret
Slaga Thomas J.
Walaszek Zbigniew
Henley III Raymond
Henry David G.
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