Chemistry: molecular biology and microbiology – Enzyme – proenzyme; compositions thereof; process for... – Oxidoreductase
Reexamination Certificate
2006-11-07
2006-11-07
Patterson, Jr., Charles L. (Department: 1652)
Chemistry: molecular biology and microbiology
Enzyme , proenzyme; compositions thereof; process for...
Oxidoreductase
Reexamination Certificate
active
07132270
ABSTRACT:
The present invention relates to improved variants of soluble pyrroloquinoline quinone (PQQ)-dependent glucose dehydrogenases (s-GDH), to genes encoding mutated s-GDH, to mutant proteins of s-GDH with improved substrate specificity for glucose, and to different applications of these s-GDH variants, particularly for determining concentrations of sugar, especially of glucose in a sample.
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Beck Daniela
Knappe Wolfgang-Reinhold
Kratzsch Peter
Schmuck Rainer
Shao Zhixin
Barnes & Thornburg LLP
Patterson Jr. Charles L.
Roche Diagnostics GmbH
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