Forms of microencapsulation of medicinal substances by homogeneo

Details Forms of microencapsulation of medicinal substances by homogeneo Forms of microencapsulation of medicinal substances by homogeneo

1984-04-03

1987-12-08

Rose, Shep K.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Capsules

424477, 424491, 424499, 106155, 106161, 530356, 514773, 514774, 514801, A61K 938, A61K 964, A61K 922, A61K 952

Patent

active

047117834

ABSTRACT:
A new sustained-release, microencapsulated pharmaceutical composition is disclosed, suitable for oral administration which contains an effective amount of an orally-administered pharmaceutical in granular form wherein the granules are coated by a layer of homogeneous, native collagen to encapsulate the granules. Also disclosed is a method for administering the sustained-release compositions and a process for covering the granulated pharmaceutical with the layer of homogeneous, native collagen.

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Biochim. Biophysica Acta., 194 (1969), pp. 325-328, Herbage et al.
J. F. Woessner, Jr., Treatise on Collagen, Biological Mechanisms of Collagen Resorption, vol. 2, pp. 253-330, (1968).
A. Veis, Int. Rev. of Connective Tissue Research, vol. 3, pp. 113-200 (1965).

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