Forms of 5-Azacytidine

Details Forms of 5-Azacytidine Forms of 5-Azacytidine

2006-07-18

2006-07-18

Jiang, Shaojia Anna (Department: 1623)

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

C536S124000, C536S063000, C536S028100, C536S023100, C536S024310, C536S024330, C536S022100, C514S049000, C514S085000, C514S269000, C424S045000, C424S450000

Reexamination Certificate

active

07078518

ABSTRACT:
The disclosure includes novel polymorphic and pseudopolymorphic crystalline forms of 5-azacytidine, along with methods for preparing said forms, wherein 5-azacytidine is represented by the formula:The disclosure also includes pharmaceutical compositions comprising said forms.

REFERENCES:
patent: 3350388 (1967-10-01), Sorm et al.
patent: 3817980 (1974-06-01), Vorbrüggen et al.
patent: 3891623 (1975-06-01), Vorbrüggen et al.
patent: 4082911 (1978-04-01), Vorbrüggen
patent: 4209613 (1980-06-01), Vorbrüggen
patent: 6723728 (2004-04-01), Hu et al.
patent: 6943249 (2005-09-01), Ionescu et al.
patent: 2004/0186284 (2004-09-01), Ionescu et al.
patent: 1922702 (1971-04-01), None
patent: 2012888 (1971-09-01), None
patent: 1227691 (1971-04-01), None
Beisler, Journal of Medicinal Chemistry, 21(2):204 (1978).
Niedballa & Vorbrüggen, Journal of Organic Chemistry, 39(25):3672 (1974).
Kornblith et al., J. Clin Oncol. 20: 2441 (2002).
Piskala & Sorm, Collect. Czech. Chem. Commun. 29:2060 (1964).
Piskala & Sorm, Nucleic Acid Chemistry 1: 435 (1978).
Piskala & Sorm, Nucleic Acids Research, Special Publication No. 1: s17 (1975).
Silverman et al., J. Clin Oncol. 20: 2429 (2002).
Vorbrüggen et al, Chem. Ber. 114: 1234 (1981).
Vorbrüggen & Bennua, Chem Ber. 114: 1279 (1981).
Vorbrüggen & Ruh-PohlenzinOrganic Reactions, vol. 55, p. 100 (L. A. Paquettc Ed., John Wiley & Sons, New York, 2000).
Winkley & Robins, Journal of Organic Chemistry, 35(2):491-495 (1970).
Wittenburg, Z. Chem. 4:303 (1964).

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