Formation of superfibronectin by BBK32 and uses therefor

Details Formation of superfibronectin by BBK32 and uses therefor Formation of superfibronectin by BBK32 and uses therefor

2008-04-18

2010-11-02

Noakes, Suzanne M. (Department: 1656)

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving antigen-antibody binding, specific binding protein...

C514S008100

Reexamination Certificate

active

07824868

ABSTRACT:
Provided herein is a method for inducing formation of a conformationally distinct superfibronectin by contacting plasma fibronectin with BBK32 protein or a BBK32 peptide and the BBK32-induced superfibronectin so formed. Also provided are methods of inhibiting endothelial cell proliferation, of treating pathophysiological conditions associated with endothelial cell proliferation and of inhibiting angiogenesis therein using the BBK32 protein, BBK32 peptide or the BBK32-induced superfibronectin.

REFERENCES:
Prabhakaran et al., “A Novel Fibronectin Binding Motif in MSCRAMMs Targets F3 Modules”, PloS ONE, vol. 4, No. 4, p. e5412 (pp. 1-10).

Affiliated with

Also associated with

Rating

Formation of superfibronectin by BBK32 and uses therefor does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Formation of superfibronectin by BBK32 and uses therefor, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Formation of superfibronectin by BBK32 and uses therefor will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-4208848