Formation of enediynes by reductive coupling followed by...

Details Formation of enediynes by reductive coupling followed by... Formation of enediynes by reductive coupling followed by...

2005-11-22

2005-11-22

Nazario-Gonzalez, Porfirio (Department: 1621)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heavy metal containing

C556S043000, C556S046000, C556S136000, C556S140000, C549S206000, C585S534000, C585S643000, C502S152000

Reexamination Certificate

active

06967256

ABSTRACT:
One aspect of the present invention relates to methods of preparing enedialkylidyne complexes, enediynes, and alkyne metathesis catalysts, as well as methods of catalyzing alkyne metathesis reactions. The present invention also relates to methods of activating enedialkylidyne complexes for metathesis. The present invention also relates to enedialkylidyne complexes.

REFERENCES:
patent: 5436361 (1995-07-01), Jones et al.
patent: 6175047 (2001-01-01), Hori et al.
patent: 6391916 (2002-05-01), Dai et al.
patent: 2002/0034829 (2002-03-01), Hall et al.
patent: 2002/0058812 (2002-05-01), Grubbs et al.
patent: 2002/0072632 (2002-06-01), Guram et al.
patent: WO 99/40047 (1999-08-01), None
patent: 1 022 282 (1999-01-01), None
Yi-Chou Tsai, et al., “Facile Synthesis of Trialkoxymolybdenum (VI) Alkylidyne Complexes for Alkyne Metathesis,”Organometallics 2000, vol. 19, pp. 5260-5262, (Jul. 27, 2000).
Philippus F. Engel, et al., “Carbon-Carbon and Carbon-Heteroatom Coupling Reactions of Metallacarbynes,”Chemical Rev. 1995, 95, pp. 2281-2309, (Jan. 27, 1994).
Karin Weiss, et al., “Acyclic Diyne Metathesis (ADIMET), an Efficient Route to Poly(phenylene)ethynylenes (PPEs) and Noncunjugated Polyalkynylenes of High Molecular Weight,”Angew. Chem. Int. Ed. Engl., 36, No. 5, pp. 506-509, (1997).
Andreas Mayr et al., “Electronic Communications between Metal Centers Across Unsaturated Alkylikyne Ligands,”J. Am. Chem. Soc., 1999, 121, pp. 1760-1761, (Feb., 1999).
Richard R. Schrock, “High Oxidation State Multiple Metal-Carbon Bonds,”Chem. Rev. 2002, 102, pp. 145-179, (2002).
Marie Pui Yin Yu, et al., “4-Iodobenzylidyne as a Precursor Ligand for Extended Unsaturated Alkylidyne Ligands”,J. Chem. Soc. Dalton Trans., pp. 2373-2378 (1988).
Graerne Hogarth, et al., “Linking Metal Centres with Diimido Ligands: Synthesis, Electronic and Molecular Structure and Electrochemistry of Organometallic Ditungsten Complexes,J. Chem Soc., Dalton Trans.,”pp. 2705-2723 (1999).
Andreas Mayr, et al., “Recent Advances in the Chemistry of Metal-Carbon Triple Bonds,”Advances in Organometallic Chemistry, vol. 32, pp. 227-324, (1991).
Frederic Paul, et al., “Organometallic Molecular Wires and Other Nanoscale-Sized Devices. An Approach Using the Organoiron (dppe)Cp*Fe Building Block”, pp. 431-509, ,Elsevier Scienc S.A., 178-180, (1998).
James M. Blackwell, et al., “Enediynes via Sequential Acetylide Reductive Coupling and Alkyne Metathesis: Easy Access to Well-Defined Molybdenum Initiators for Alkyne Metathesis,”Organometallics 2003, 22, pp. 3351-3353 (2003).
David S. Frohnapfel, et al., “Variable Electronic Coupling Through Hydrocarbon Spacers Bridging-Carbon Triple”J. Phys. Chem A 1998. 102. pp. 5665-5669, (1998).
Keng-Yu Shih, et al., “Synthesis of Molybdenum Complexes that Contain Silylated Triamidoamine Ligsands. A μ-Dinitrogen Complex, Methyl and Acetylide Complexes, and Coupling of Acetylides,”J. Am. Chem. Soc. 1994, 116, pp. 8804-8805, (1994).
Steven A. Krouse, et al. “The Synthesis oftrans-(Me3CO)3W≡CCH≡CHC≡W (OCMe3)3,cis,cis-(Me3CO)3W≡CCH≡CHC≡CCh≡CHC≡W (OCMe3)3,”Journal of Organometallic Chemistry, 355, pp. 257-265, (1988).
B. E. Woodworth, et al., “Stepwise Synthesis of (≡CCH2CH2C≡), (≡CCH≡CHC≡), and (≡CC≡CC≡) Bridges between Molybdenum or Tungsten Centers,”J. Am. Chem. Soc. 1997, 119, pp. 828-829, (1996).
Hai Ping Xia, et al., “Synthesis of Symmetrical C5H5-Bridged Dimeric Ruthenium Complexes,”Organometallics 1997, 16, pp. 3557-3560, (1997).
Blackwell, J. M. et al., “Enediynes via Sequential Acetylide Reductive Coupling and Alkyne Metathesis: Easy Access to Well-Defined Molybdenum Initiators for Alkyne Metathesis,”Amer. Chem. Soc. Organometallics, 22, 3351-3353 (2003).
Krouse, S. A. et al., “The synthesis oftrans-(Me3CO)3W≡CCH≡CHC≡W(OCMe3)3,cis,cis-(Me3CO)3W≡CCH≡CHC≡CCH≡CHC≡W(OCMe3)3, and related metal-capped ene-ynes, and evaluation of them as catalysts for preparing polydiacetylenes,”Journal of Organometallic Chem, 355, 257-265 (1988).
International Search Report completed on Sep. 10, 2004 and mailed on Sep. 20, 2004.

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