Formation of adjuvant complexes

Details Formation of adjuvant complexes Formation of adjuvant complexes

1989-10-24

1991-01-01

Moskowitz, Margaret

Drug, bio-affecting and body treating compositions

Lymphokine

530403, 530405, 530406, A61K 3900

Patent

active

049816845

ABSTRACT:
"Iscom" adjuvant matrices, comprising a sterol, a glycoside, a solubilized water-insoluble antigen and, optionally, a phospholipid, may be formed without removing the solubilizing agent used for the antigen. The glycoside is preferably Quil A and the sterol is preferably cholesterol.

REFERENCES:
patent: 4578269 (1986-03-01), Morein
Morein, B. et al., (1984), Nature 308, 457-460.

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