Formamido cephalosporin compounds

Details Formamido cephalosporin compounds Formamido cephalosporin compounds

1972-03-28

1977-03-22

Rizzo, Nicholas S.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

424246, C07D50120

Patent

active

040136450

ABSTRACT:
Protection of the amino group of a 7.beta.-aminoceph-4-carboxylic acid or derivative thereof while at least one reaction is being carried out to introduce a desired group at at least one of the positions 1, 2, 3 and 4 by first converting the amino group to a formamido group and then regenerating the amino group after the desired group has been introduced. Novel intermediates may be produced which are compounds of the formula ##STR1## wherein R is C.sub.1 -C.sub.4 alkyl and Z is --O--, --S--, ##STR2## or salts or esters thereof.

REFERENCES:
patent: 3445463 (1969-05-01), Van Heyningen et al.
patent: 3446803 (1969-05-01), Van Heyningen et al.

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