Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1997-09-02
1999-05-04
Chang, Ceila
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
546197, A61K 31445, C07D40512
Patent
active
059004231
ABSTRACT:
"Paroxetine hydrochloride (I) anhydrate ##STR1## free of bound propan-2-ol, and various forms thereof, are useful in the treatment of depression and other disorders for which administration of selective serotonin reuptake inhibitors are indicated."
REFERENCES:
patent: 3912743 (1975-10-01), Christensen
patent: 4007196 (1977-02-01), Christensen et al.
patent: 4721723 (1988-01-01), Barnes et al.
patent: 4745122 (1988-05-01), Lassen
patent: 5672612 (1997-09-01), Ronsen et al.
Buxton et al. "Infrared spectroscopic studies on the solid State Forms of paroxetine hydrochloride" Anal. Proc. v.25, pp. 305-306, 1988.
Fox et al. "Physics and chemistry of the organic solid state", Interscience Pub. pp. 181-182, 1963.
Buxton et al., International Journal of Pharmaceutics, 42, pp. 135-143 (1988).
Buxton, et al., "Solid-State Forms of Paroxetine Hydrochloride", Publication presented at meeting of Joint Pharmaceutical Analysis Group in London on Oct. 8, 1987.
Wennogle, et al., Life Sciences, vol. 36, pp. 1541-1550 (1985).
Fuller et al., Neuropharmacology, 23(5), pp. 539-544 (1984).
Hwang et al., Cummunication in Psychopharmacol., vol. 4, pp. 161-167 (1980).
Lund et al., Acta Pharmacol. Toxicol., vol. 44, pp. 289-295 (1979).
Middlemiss, Maunyn-Schmiedeberg's Arch. Pharmacol., vol. 327, pp. 18-22 (1984).
Laursen et al., Acta Psychiatr. Scand., vol. 71, pp. 249-255 (1985).
Lynch et al., "Infrared Spectoscopic Studies on the Solid State Form of Paroxetine Hydrochloride", Analytical Proceedings, vol. 25, pp. 305-306 (1988).
Hair et al., "Gels and Foams From Ultrahigh-Molecular Weight Polyethylene", Chemical Abstracts, 110:58945.
Evans, An Introduction to Crystal Chemistry, Cambridge Press, pp. 393-397.
Hanney, "Treatise on Solid State Chemistry", Plenum Press, pp. 89-90.
Jacewicz Victor Witold
Ward Neal
Chang Ceila
Lentz Edward T.
SmithKline Beecham Corporation
LandOfFree
Form of paroxetine hydrochloride anhydrate does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Form of paroxetine hydrochloride anhydrate, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Form of paroxetine hydrochloride anhydrate will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1869677