Form of N-(trans-4-isopropylcyclohexylcarbonyl)-D-phenylalanine

Organic compounds -- part of the class 532-570 series – Organic compounds – Carboxylic acids and salts thereof

Reexamination Certificate

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Details

C562S444000, C562S445000, C514S563000

Reexamination Certificate

active

07314955

ABSTRACT:
The present invention relates to a novel crystalline form of N-(trans-4-isopropylcyclohexylcarbonyl)-D-phenylalanine and methods for preparing the same.

REFERENCES:
patent: 4816484 (1989-03-01), Toyoshima et al.
patent: 5463116 (1995-10-01), Sumikawa et al.
patent: 5488150 (1996-01-01), Sumikawa et al.
patent: 196 222 (1986-10-01), None
patent: WO-03/093222 (2003-11-01), None
Chemical Abstracts 136:159110; Li et al.: “A new crystal structure in nateglinide found by X-ray powder diffraction”; Yaowu Fenxi Zazhi (2001), 21(5), 342-44, Abstract.
Shinkai et al., “N-(Cyclohexylcarbonyl)-D-phenylalanines and Related Compounds. A New Class of Oral Hypoglycemic Agents, 2”,J. Med. Chem., 32(7): 1436-41, 1989.
International Search Report, PCT/IN02/00114, Sep. 5, 2002.
Written Opinion, PCT/IN02/00114, date of mailing Jun. 23, 2003.

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