Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...
Patent
1995-06-02
1996-06-04
Ivy, C. Warren
Organic compounds -- part of the class 532-570 series
Organic compounds
Heterocyclic carbon compounds containing a hetero ring...
C07D30752
Patent
active
055234232
ABSTRACT:
Process for the production of an improved form of Form 1 Ranitidine Hydrochloride having improved filtration and drying characteristics, said process comprising in a substantially anhydrous hydroxylic solvent, comprising at least one alkanol solvent having 3-4 carbon atoms, adding anhydrous hydrogen chloride gas to Ranitidine free base wherein said substantially anhydrous hydroxylic solvent has the characteristics that it solubilizes the Ranitidine free base and hydrogen chloride gas, and subsequently recovering the improved form of Form 1 Ranitidine Hydrochloride.
REFERENCES:
patent: 4128658 (1978-12-01), Price et al.
patent: 4521431 (1985-06-01), Crookes
patent: 4672133 (1987-06-01), Crookes
Murthy Keshava
Radatus Bruno K.
Swidhu Kanwarpal S.
ACIC (Canada) Inc.
Hughes Ivor M.
Hughes Neil H.
Ivy C. Warren
Owens Amelia
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