Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...
Patent
1999-07-26
2000-09-19
McKane, Joseph
Organic compounds -- part of the class 532-570 series
Organic compounds
Heterocyclic carbon compounds containing a hetero ring...
548537, 548560, 548561, 548562, C07D207327, C07D207333, C07D207335
Patent
active
061214612
ABSTRACT:
A novel crystalline form of [(R-(R*,R*)]-2-(4-fluorophenyl)-.beta.,.delta.-dihydroxy-5-(1-methylethyl) -3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrole-1-heptanoic acid hemi calcium salt designated Form III is characterized by its X-ray powder diffraction and/or solid state NMR is described, as well as methods for the preparation and pharmaceutical composition of the same, which is useful as an agent for treating hyperlipidemia and hypercholesterolemia.
REFERENCES:
patent: 5316765 (1994-05-01), Folkers et al.
Tetrahedron Letters, vol. 33, No. 17, 1992, pp. 2283-2284, Baumann, et al.
Pharmaceutical Research, vol. 10, No. 10, 1993, pp. 1461-1465, Kearney, et al.
Atherosclerosis, vol. 111, 1994, pp. 127-142, Bocan, et al.
Tetrahedron Letters, vol.33, No. 17, 1992, pp 2283-2284, Baumann, et al.
Pharmaceutical Research, vol. 10, No. 10, 1993, pp 1461-1465, Kearney, et al.
McKane Joseph
Oswecki Jane C.
Tinney Francis J.
Warner-Lambert & Company
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