Foot and mouth disease virus vaccine comprising interferons

Details Foot and mouth disease virus vaccine comprising interferons Foot and mouth disease virus vaccine comprising interferons

2002-04-24

2011-11-15

Kelly, Robert M (Department: 1633)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

C424S093200, C536S023100, C536S023520

Reexamination Certificate

active

08058248

ABSTRACT:
Early protection of susceptible animals against foot and mouth disease (FMD) may be achieved by inoculating the animals with a vaccine comprising an interferon DNA sequence. One day after inoculation, animals have been found protected from challenge with virulent foot and mouth disease virus. Co-administration with an effective foot and mouth disease virus vaccine provides protection prior to the development of specific immunity, a feature especially desireable during a FMD outbreak.

REFERENCES:
patent: 4795436 (1989-01-01), Robinson
patent: 5612040 (1997-03-01), Mason et al.
patent: 5672510 (1997-09-01), Eglitis et al.
patent: 5739118 (1998-04-01), Carrano et al.
patent: 5814482 (1998-09-01), Dubensky, Jr. et al.
patent: 5824316 (1998-10-01), Grubman et al.
patent: 5831023 (1998-11-01), Capon et al.
patent: 6045802 (2000-04-01), Schlom et al.
patent: 6066624 (2000-05-01), Woo et al.
patent: 6221361 (2001-04-01), Cochran et al.
patent: 6544780 (2003-04-01), Wang
Ahmed, et al. (1999) Hum. Gene Therapy 10(1): 77-84.
Knipe, et al. (2001) Fundamental Virol., 4th Ed., Lippincott, Williams & Wilkins, Philadelphia, PA, pp. 534, 1091.
Gorecki (2001) Expert Opin. Emerg. Drugs 6(2): 187-98.
Verma, et al. (1997) Nature 398:239-42.
Eck, et al. (1996) The Pharmacological Basis of Therapeutics, 9th Ed., by McGraw-Hill, NY. pp. 77-101.
Nakano, et al. (1997) J. Virol. 71(9): 7101-09.
Torres, et al. (1995) Virology, 213: 503-516.
Hammond, et al. (2001) Vaccine, 19: 3752-58.
Shi, et al. (2001) J. Virology, 75(23): 11474-82.
Pettersson, et al. (2000) Laboratory Investigation, 80(1): 99-115.
Mittal, et al. (1996) Virology, 222: 299-309.
Raz, et al. (1994) Proc. Natl. Acad. Sci., USA., 91: 9519-23.
Weiss, et al. (2000) Infection and Immunity, 68(10): 5914-19.
van Rooij, et al. (1998) Vet. Immunol. Immunopath., 66: 113-26.
Muller, et al. (1998) J. Virol., 72(1): 20-31.
Dufour, et al. (2000) J. Interferon and Cytokine Research, 20: 889-895.
Cunliffe, et al. (1997) Can. J. Comp. Med., 41: 117-121.
Konishi, et al. (2000) Virology, 268: 49-55.
Moraes, M. P. et al., “Early protection against homologous challenge after a single dose of replication-defective human adenovirus type 5 expressing capsid proteins of foot-and-mouth disease virus (FMDV) strain A24”,Vaccine, vol. 20, pp. 1631-1639, 2002.
Moraes, M. P. et al., “pAd5-Blue: Direct Ligation System for Engineering Recombinant Adenovirus Constructs”,BioTechniques, vol. 31, (5), pp. 1-4, Nov. 2001.
Mayr, G. et al., “Immune responses and protection against foot-and-mouth disease virus (FMDV) challenge in swine vaccinated with adenovirus-FMDV constructs”,Vaccine, vol. 19, pp. 2152-2162, 2001.
Mayr, G. et al., “Development of Replication-Defective Adenovirus Serotype 5 Containing the Capsid and 3C Protease Coding Regions of Foot-and-Mouth Disease Virus as a Vaccine Candidate”,Virology, vol. 263, pp. 496-506, 1999.
Vilcek, J. et al., “Interferons and Other Cytokines”,Virology, Chapter 13, pp. 375-399, 1996.
Chinsangaram, J. et al., “Inhibition of L-Deleted Foot-and-Mouth Disease Virus Replication by Alpha/Beta Interferon Involves Double-Stranded RNA-Dependent Protein Kinase”,Journal of Virology, vol. 75, (12), pp. 000-000, Jun. 2001.
Chinsangaram, J. et al., “Ability of Foot-and-Mouth Disease Virus to Form Plaques in Cell Culture Is Associated with Suppression of Alpha/Beta Interferon”,Journal of Virology, vol. 73, pp. 9891-9898, 1999.

Affiliated with

Also associated with

Rating

Foot and mouth disease virus vaccine comprising interferons does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Foot and mouth disease virus vaccine comprising interferons, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Foot and mouth disease virus vaccine comprising interferons will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-4278378