Food additive intended for human consumption and as animal feed

Food or edible material: processes – compositions – and products – Dormant ferment containing product – or live microorganism...

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Details

424 931, 424 932, 424 933, 424 9345, 424 9346, 99452, 435200, 4352521, 4352529, A23C 912, A01N 6300, C12N 924, A01J 1100

Patent

active

055209360

DESCRIPTION:

BRIEF SUMMARY
FIELD OF THE INVENTION

The present invention relates to a new microbial food additive, to its application as bioregulator both in food for human consumption and in animal feed as well as to foodstuffs containing it.


BACKGROUND OF THE INVENTION

Generally, for the purposes of the present invention, a bioregulator is a product which contributes to the digestive and microbial balance of the intestine. The latter is essentially of microbial origin and there may be mentioned among the most widely known for which this bioregulatory activity has been demonstrated: Bifidobacterium, some Clostridium and Bacillus;
They are used, according to the foodstuffs into which they are incorporated and according to the desired effect, alone or in combination, and in this latter case, in particular for their symbiotic effect.
There may be mentioned, by way of examples of bioregulators used in food for human consumption, the microorganisms used in fermented milks, mainly the bacteria in yogurt or similar products (combination of Lactobacillus bulgaricus, Streptococcus thermophilus, Lactobacillus acidophilus, Bifidobacteria, and the like), or kefir grains (natural combination of bacteria and yeasts); there may be mentioned by way of examples of bioregulators used in animal feed, some Bacillus such as Bacillus toyoi, Bacillus cereus or a symbiotic mixture of Streptococcus and Lactobacillus as described in European Patent Application No. 0,406,117.


SUMMARY OF THE INVENTION

A first aspect of the present invention is an isolated strain of Sporolactobacillus having Collection Nationale de Culture de Microorganisms of Institute Pasteur Deposit No. I-1089.
A second aspect of the present invention is a microbial food additive for human consumption or as animal feed, which contains an isolated strain of either Sporolactobacillus inulinus or Sporolactobacillus P44.
A third aspect of the present invention is a microbial food additive consisting of the Sporolactobacillus P44 strain having Collection Nationale de Culture de Microorganisms of Institute Pasteur Deposit No. I-1089.
A further aspect of the present invention is a microbial food additive consisting of an association of Sporolactobacillus P44 and Sporolactobacillus inulinus, acting in symbiosis.
A further aspect of the present invention is supplemented foodstuffs for use as animal feed or for human consumption, which foodstuffs contain a microbial food additives containing an isolated strain of either Sporolactobacillus inulinus or Sporolactobacillus P44.


BRIEF DESCRIPTION OF THE DRAWING

FIG. 1 is a profile for the fermentation of sugars by the Sporolactobacillus P44 strain.


DETAILED DESCRIPTION OF THE INVENTION

Numerous hypotheses and mechanisms have been proposed to explain the bioregulatory role of these microorganisms; among the mechanisms proposed, there may be mentioned in particular: proliferation of pathogenic bacteria by producing organic acids, antibiotics, by detoxifying bacterial enterotoxins or by using the production of toxic metabolites. However, the precise role of each of these factors is difficult to evaluate because many studies performed in vitro are difficult to transpose to the human or animal intestinal tract and currently no human experimentation makes it possible to assert an antimicrobial effect in vivo, absorption of yogurts and consequently of the strains present in yogurt (Lactobacillus bulgaricus, Streptococcus thermophilus) by axenic mice resulted in a substantial increase in the quantity of immunoglobulin G and in the presence of live Lactobacillus in the mesenteric ganglia, portion of the lactose ingested in the small intestine, thus resulting in supplementation of the defective endogenous lactose, lactase. It has been shown that a change in the intestinal microflora might be responsible for the disaccharide activities of the small intestine.
Indeed, in order to be assimilated, the lactose present in the intestinal lumen should be hydrolysed by a glycoprotein situated at the surface of enterocytes, known as lactase. This hydrolysis is es

REFERENCES:
patent: 3262862 (1966-07-01), Kitahara
Botha et al. "Resistance of Sporolactobacillus . . . ", Int. J. Food Microbiol. 5(4) p. 331-336 (1987).
T. Masaki et al., "Continuous Production of D-Lactate by a Hollow Fiber Bioreactor", Chemical Abstracts, vol. 111, No. 17, Oct. 23, 1989, Abstract No. 152007F, p. 565.
R. Gherna et al., American Type Culture Collection, Catalogue of Bacteria and Phages, Seventeenth Edition, 1989, col. 2, lines 42-47, p. 201.
T. Karki et al., "Microorganisms Associated with Various Pickles", Biological Abstracts, vol. 79, No. 3, 1985, p. AB-326.
S. Doores et al., "Heat Resistance of Sporolactobacillus inulinus", Journal of Food Science, vol. 46, No. 3, 1981, pp. 810-812.

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