Folliculotropin releasing hormone

Details Folliculotropin releasing hormone Folliculotropin releasing hormone

1972-12-13

1976-03-16

Padgett, Benjamin R.

Drug, bio-affecting and body treating compositions

Radionuclide or intended radionuclide containing; adjuvant...

Molecular bilayer structure

424 95, 23230B, A61k 2704, A61k 1708

Patent

active

039446590

ABSTRACT:
A method for producing the Folliculotropin Releasing Hormone (FRH) biosynthetically is provided by utilizing, as key starting materials, fresh hypothalamic tissue, a buffered incubation medium, an ATP synthesizing system, radioactively labeled amino acids and a mixture of 21 naturally occuring amino acids. Biosynthesis of the FRH is accomplished by incubation of the hypothalamic tissue for a short period of time in the presence of all the reagents necessary to promote the biosynthetic system to produce the Folliculotropin Releasing Hormone (FRH) of the hypothalamus gland of mammals. Examples of methods to isolate the FRH free of the luteotropin releasing hormone (LRH) are provided.

REFERENCES:
sievertsson et al., Biochemical and Biophysical Research Communications, Vol. 44, No. 6, (1971), pp. 1566-1571.
Matsuo et al., Biochem. & Biophys. Res. Comm., Vol. 43, No. 6, (1971), pp. 1334-1339.

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