Folic acid derivatives and use in radio-assay

Details Folic acid derivatives and use in radio-assay Folic acid derivatives and use in radio-assay

1974-08-09

1976-11-02

Gotts, Lewis

Drug, bio-affecting and body treating compositions

Radionuclide or intended radionuclide containing; adjuvant...

Molecular bilayer structure

2601125R, 23230B, 206 84, A61K 4300, C07C10352, A61N 512

Patent

active

039898121

ABSTRACT:
Novel folic acid derivatives useful for radio-assaying folic acid and its metabolites in biological liquids are prepared from pteroyl-.gamma.-glutamyl-tyrosines by iodination with I.sup.125 or I.sup.131.

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Boothe et al.: J. Am. Chem. Soc., 70, pp. 1099-1102 (1948).
Boothe et al.: J. Am. Chem. Soc., 71, pp. 2304-2308 (1949).
Cooperman et al.: Chem. Abstr. 67:71459a (1967).
Rothenberg et al.: Chem. Abstr. 74:96929m (1971).
Mitta et al.: Chem. Abstr. 68:69303x (1968).
Radichevich et al.: Chem. Abstr. 67:506c (1967).

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