Fluorous triphase and other multiphase systems

Organic compounds -- part of the class 532-570 series – Organic compounds – Silicon containing

Reexamination Certificate

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C556S450000, C556S476000, C556S485000

Reexamination Certificate

active

06897331

ABSTRACT:
A method of reacting a first non-fluorous compound to produce a second non-fluorous compound includes the steps of: contacting a first non-fluorous phase including the first non-fluorous compound with a first fluorous phase at a first phase interface, the first non-fluorous compound distributing between the first fluorous phase and the first non-fluorous phase; contacting the first fluorous phase with a second non-fluorous phase at a second phase interface; and including at least a third non-fluorous compound in the second non-fluorous phase that reacts with the first non-fluorous compound to produce the second non-fluorous compound, the second non-fluorous compound having a distribution coefficient less than the first non-fluorous compound. For example, the first non-fluorous compound can be dibromine or diiodine, and the second non-fluorous compound can be an alkene.

REFERENCES:
patent: 4454233 (1984-06-01), Wang
patent: 5401847 (1995-03-01), Glazer et al.
patent: 5463082 (1995-10-01), Horvath et al.
patent: 5777121 (1998-07-01), Curran et al.
patent: 5798032 (1998-08-01), Khan et al.
patent: 5859247 (1999-01-01), Curran et al.
patent: 6156896 (2000-12-01), Curran et al.
patent: WO 02100802 (2002-12-01), None
Barthel-Rosa, L. P.; Gladysz, J. A. Chemistry in Fluorous Media: A User's Guide to Practical Considerations in theApplication of Fluorous Catalysts and Reagents. Coord. Chem. Rev.; 190-192;(1999), 587-605.
Cavazzini, M.; Montanari, F.; Pozzi, G.; Quici, S. Perfluorocarbon-Soluble Catalysts and Reagents and the Application of FBS (FluorousBiphase System) to Organic Synthesis J. Fluorine Chem.; 94 (1999); 183-193.
Chang, S. K; Hamilton, A. D., Molecular Recognition of Biologically Interesting Substrates: Synthesis of Artificial Receptors for Barbituates Employing Six Hydrogen Bonds J. Am. Chem. Soc., 1988, 110, 1318-1319.
Curran, D. P. Strategy-Level Separations in Organic Synthesis: From Planning to Practice. Angew. Chem., Int. Ed. Eng. 1998, 37, 1176-1196.
De Wolf, E.;Van Koten, G.; Deelman, B-J. Fluorous Phase Separation Techniques in Catalysis. Chem. Soc. Rev. 1999, 28, 37-41.
Fish, R. H. Fluorous Biphasic Catalysis: A New Paradigm for the Separation of Homogeneous Catalysts from their Reaction Substrates and Products. Chem. Eur.J. 1999, 5, 1677-1680.
Hope, E. G.; Stuart. A. M. Fluorous Biphase Cataysis. J. Fluorine Chem.; 100; (1999); 75-83.
Horvath, I. T. Fluorous Biphase Chemistry. Acc. Chem. Res. 1998, 31, 641-650.
Pereira, S. M. et al.; Perfluorohexane as a Nobel Reaction Medium for Bromination Reactions; Synth. Commun; 1995; 25; 1023-1026.
Zhu, D-W; A Novel Reaction Medium: Perfluorocarbon Fluids; Synthesis; 1993;953-954.

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