Fluoronitroaralkyloxazolines, derivatives thereof, and nucleophi

Details Fluoronitroaralkyloxazolines, derivatives thereof, and nucleophi Fluoronitroaralkyloxazolines, derivatives thereof, and nucleophi

1983-02-25

1985-09-10

Daus, Donald G.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

560102, 260465D, C07D26310

Patent

active

045407959

ABSTRACT:
Fluoronitroaralkyloxazolines are prepared by reacting a fluoronitroaromatic compound with an alpha-substituted 2-alkyloxazoline in an inert solvent and in the presence of a base. Fluoronitroaralkyloxazolines are useful intermediates for the synthesis of pharmaceuticals, such as flurbiprofen.

REFERENCES:
patent: 3641040 (1972-02-01), Carney et al.
patent: 3657230 (1972-04-01), Carney et al.
patent: 3755427 (1973-08-01), Adams et al.
patent: 3767805 (1973-10-01), Carney et al.
patent: 3868391 (1975-02-01), Carney et al.
patent: 3901906 (1975-08-01), Kozlik
patent: 3936467 (1976-02-01), Carney et al.
patent: 3959364 (1976-05-01), Armitage et al.
patent: 3993763 (1976-11-01), Carney et al.
patent: 3997669 (1976-12-01), Carney et al.
patent: 4010274 (1977-03-01), Giraldi et al.
patent: 4126691 (1978-11-01), Carney et al.
patent: 4163788 (1979-08-01), Carney et al.
patent: 4239901 (1980-12-01), Rainer
patent: 4266069 (1981-05-01), Walker
patent: 4278516 (1981-07-01), Zaiko et al.
patent: 4324904 (1982-04-01), Hylton et al.
patent: 4370278 (1983-01-01), Stahly et al.
Morrison and Boyd, "Organic Chemistry", 3rd Ed., pp. 737-738, Allyn and Bacon, Inc., Boston (1973).
Burger, A., Medicinal Chemistry, 2nd Ed., p. 42, Interscience Publishers, Inc., N.Y., (1960).

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