Fluorometric detection using visible light

Radiant energy – Luminophor irradiation

Reexamination Certificate

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Reexamination Certificate

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06914250

ABSTRACT:
Systems, devices and methods of the present invention are for viewing a pattern of fluorophors capable of fluorescing when exposed to visible light, e.g., fluorescently stained DNA, protein or other biological material. The system includes a light source emitting light in the visible spectrum, such as a fluorescent lamp used in domestic lighting, a first optical filter capable of transmitting light from the source at wavelengths capable of exciting the fluorophors and of absorbing light of other wavelengths, and a second optical filter capable of blocking substantially all the light from the source not blocked by the first filter, so that the only light reaching the viewer is light produced by fluorescence of the fluorophors.

REFERENCES:
patent: 2113973 (1938-04-01), Addink
patent: 3802102 (1974-04-01), Licciardi
patent: 4071883 (1978-01-01), Dennis
patent: 4117338 (1978-09-01), Adrion et al.
patent: 4266535 (1981-05-01), Moret
patent: 4906100 (1990-03-01), Rice et al.
patent: 5108179 (1992-04-01), Myers
patent: 5274240 (1993-12-01), Mathies et al.
patent: 5306144 (1994-04-01), Hibst et al.
patent: 5315375 (1994-05-01), Allen
patent: 5324940 (1994-06-01), Ekstrom
patent: 5327195 (1994-07-01), Ehr
patent: 5347342 (1994-09-01), Ehr
patent: 5363854 (1994-11-01), Martens et al.
patent: 5387801 (1995-02-01), Gonzalez et al.
patent: 5543018 (1996-08-01), Stevens et al.
patent: 5736744 (1998-04-01), Johannsen et al.
patent: 5742066 (1998-04-01), Cavestri
patent: 5760407 (1998-06-01), Margosiak et al.
patent: 5856866 (1999-01-01), Shimizu et al.
patent: 6161323 (2000-12-01), Kageyama
patent: 6198107 (2001-03-01), Seville
patent: 6512236 (2003-01-01), Seville
patent: 2117345 (1993-07-01), None
patent: 2136209 (1993-11-01), None
patent: 2093532 (1994-10-01), None
patent: 2197068 (1996-02-01), None
patent: 2207488 (1996-06-01), None
patent: 2171588 (1996-09-01), None
patent: 2234950 (1997-05-01), None
patent: 2251809 (1997-10-01), None
patent: 2253403 (1997-11-01), None
patent: 0 603 783 (1994-06-01), None
patent: 10-132744 (1998-05-01), None
patent: 10-274637 (1998-10-01), None
Jenkins, F.A. and White, H.E.,Fundamentals of Optics(4thed.) McGraw-Hill, Toronto 1976, pp. 503-504.
Herolab (Apr. 1995), “Gel-Dokumentation and Analyse,” pp. 1-3.
UVP (Jun. 1991), “Product Catalog”, pp. 1-7 and 9-12.
UVP International Ultra-Violet Products, (Feb. 1990), “New Products,” UVP International Newsletter, 4 pp.
Herolab GMBH, (Aug. 1995), “Produktkatalog,”Herolab Highlights,1:1-7, XP002158317.
Brunk, C.F. and Simpson, L., (Oct. 1977), “Comparison of Various Ultraviolet Sources for Fluorescent Detection of Ethidium Bromide-DNA Complexes in Polyacrylamide Gels,”Analytical Biochemistry82:455-462.
Golden, Gregory S., (May 1994), Use of Alternative Light Source Illumination in Bite Mark Photography,J. Forensic Sciences,39:815-823.
Gründemann, D. and Schömig, E., (Nov. 1996), “Protection of DNA During Preparative Agarose Gel Electrophoresis Against Damage Induced by Ultraviolet Light,”BioTechniques21:898-903.
Haughland, R.P., “Hand Book of Fluorescent Probes and Research Chemicals,” (1996)6th, Edition, Michelle T.Z. Spence, Ed., Molecular Probes Inc., Eugene OR,pp. 13-18, 25-28 and 29-35.
Menzel, E.R., (1991), “An Introduction to Lasers, Forensic Lights and Fluorescent Fingerprint Detection Techniques,”Lightning Powder Company, Inc., Salem OR.
Neri et al., (Apr. 1996), “Multipurpose High Sensitivity Luminescence Analyzer (LUANA): Use in Gel Electrophoresis,”BioTechniques20(4):708-713.
Payton Scientific Inc. website—http://home.att.net/˜paytonscientific/page6.html, pp. 1-2, date of publication unknown (downloaded Jul. 21, 1999).
Payton Scientific Inc. website—http://home.att.net/˜paytonscientific/page14.html, pp. 1-2, date of publication unknown (downloaded Jul. 21, 1999.
Payton Scientific Inc. website—http://home.att.net/˜paytonscientific/page7.html, pp. 1-2, date of publication unknown (downloaded Jul. 21, 1999).
Payton Scientific Inc. website—http://home.att.net/˜paytonscientific/page8.html, pp. 1-2, date of publication unknown (downloaded Jul. 21, 1999).
Payton Scientific Inc. website—http://home.att.net/˜paytonscientific/index.html, pp. 1-3, date of publication unknown (downloaded Jul. 21, 1999).
Rofin Forensic Product website—http://rofin.com.au/pr-fp.htm, pp. 1-8, date of publication unknown (downloaded Jul. 6, 1999).
Sharp, P.A. et al., (1973), “Detection of Two Restriction Endonucleases Activities inHaemophilus parainfluenzaeUsing Analytical Agarose-Ethidium Bromide Electrophoresis,”Biochemistry12(16):3055-3063.
Stoilovic, Milutin, (1991), “Detection of Semen and Blood Stains Using Polilight as a Light Source,”Forensic Science International51:289-296.
Ünlü et al., (Oct. 1997), “Difference gel electrophoresis: A single gel method for detecting changes in protein extracts,”Electrophoresis18:2071-2077.

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