Chemistry: analytical and immunological testing – Optical result – With fluorescence or luminescence
Patent
1997-11-12
2000-09-05
Warden, Jill
Chemistry: analytical and immunological testing
Optical result
With fluorescence or luminescence
436 60, 436 71, 436 86, G01N 2164
Patent
active
061141771
ABSTRACT:
A method for measuring total antioxidant activity of antioxidants utilizes BODIPY dyes which fluoresce in the visible region of the electromagnetic spectrum as a fluorescent reporter.
REFERENCES:
patent: 4269938 (1981-05-01), Frank
patent: 4774339 (1988-09-01), Haugland et al.
patent: 5338854 (1994-08-01), Kang et al.
patent: 5372936 (1994-12-01), Fraatz et al.
patent: 5395755 (1995-03-01), Thorpe et al.
patent: 5460943 (1995-10-01), Hayashi et al.
patent: 5554502 (1996-09-01), Mithuhashi et al.
patent: 5605809 (1997-02-01), Komoriya et al.
patent: 5614386 (1997-03-01), Metzker et al.
patent: 5762930 (1998-06-01), Fanger et al.
patent: 5804395 (1998-09-01), Schade et al.
Holler, Tod. P.; Hpkins, Paul B. "A Qualitative Fluorescence-Based Assay for Tyrosyl Radical Scavenging Activity: Ovothiol A is an Efficient Scavenger." Analytical Biochemistry, 326-330, Aug. 1989.
Tsuchiya, M.; Scita, G.; Freisleben, H.; Kagan, V.; and Packer, L. "Antioxidant Radical-Scavenging Activity of Carotenoids and Retinoids Compared to alpha-Tocopherol." Methods in Enzymology, 460-472, 1992.
Karolin, J; Johansson, L.; Strandberg, L.; and Ny, T. "Fluorescence and Absorption Spectroscopic Properties of Dipyrrometheneboron Difluoride (BODIPY) Derivatives in Liquids, Lipid Membrances, and Proteins." J. Am. Chem. Soc., 7801-7806, Aug. 1994.
Park, D. K.; and Song, J. H. "Determination of the Antioxidant Activity of Vitamins C and E According to Lipid Physical State Using High Performance Liquid Chromatography with Chemiluminescence Detection." Korean Biochem. J., 473-478, 1994.
Makrigiorgos, G. M. "Detection of Lipid Peroxidation on Erythrocytes Using the Excimer-Forming Property of a Lipophilic BODIPY Fluorescent Dye." Biochem. and Biophys. Methods, 23-35, Aug. 1997.
Kang, M. Y.; Tsuchiya, M.; Packer, L.; and Manabe, M. "In Vitro study on Antioxidant Potential of Various Drugs Used in the Perioperative Period." Acta Anaesthesiologica Scand. 4-12, 1998.
Phytochem Technologies, Inc.
Warden Jill
LandOfFree
Fluorometric assay for measurement of antioxidant activity does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Fluorometric assay for measurement of antioxidant activity, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Fluorometric assay for measurement of antioxidant activity will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-2211272