Fluoromethylthiooxacephalosporins

Details Fluoromethylthiooxacephalosporins Fluoromethylthiooxacephalosporins

1983-12-22

1985-07-30

Raymond, Richard L.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Silicon containing doai

514186, 514191, 514210, 544 64, 544 69, 544 90, A01N 4390, C07D49804

Patent

active

045322333

ABSTRACT:
An antibacterial 7.beta.-(fluorinated methylthioacetamido)-7.alpha.-methoxy-3-(1-hydroxyalkyl-5-tetrazolyl)thiom ethyl-1-dethia-1-oxa-3-cephem-4-carboxylic acid and its derivatives at the carboxy or hydroxyalkyl represented by the following formula: ##STR1## wherein, R is FCH.sub.2 -- or F.sub.2 CH--; R.sup.1 is R.sup.3 O-substituted-alkyl in which R.sup.3 is hydrogen or a hydroxy-protecting group; and R.sup.2 is a hydrogen or light metal atom or a carboxy-protecting group, antibacterial drugs containing it, its use and production.

REFERENCES:
patent: 4232151 (1980-11-01), Nagata et al.
patent: 4371532 (1983-02-01), Narisada et al.

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