Fluorogenic trypotophanase substrates

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

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549224, 549225, 549227, 549288, 560100, 562490, 564196, 564204, 435772, C07D31190, C07D31116

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050555944

ABSTRACT:
A fluorogenic substrate for tryptophanase useful for identifying an unknown microorganism is a fluorescent dye linked to an amino acid by a carbamate or thiocarbamate group. In preferred substrates, the dye is fluorescein or 7-amino-4-methyl coumarin and the amino acid linked thereto is cysteine, threonine or serine.

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Shute et al., Synthesis, 1987, 346.

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