Fluorogenic dyes

Details Fluorogenic dyes Fluorogenic dyes

2006-04-11

2006-04-11

Le, Long V. (Department: 1641)

Chemistry: analytical and immunological testing

Optical result

With fluorescence or luminescence

C436S528000, C436S529000, C436S531000, C436S532000, C436S533000, C436S534000, C436S537000, C436S546000, C436S063000, C436S091000, C436S111000, C436S112000, C436S119000, C436S120000, C436S126000, C436S129000, C436S800000, C435S007100, C435S007600, C435S007800, C435S459000, C435S177000, C435S178000, C435S180000, C435S181000, C435S188000, C435S961000, C435S091500, C435S091500, C435S091500, C435S091500, C435S091500, C435S091500, C424S009600, C424S707000, C424S278100

Reexamination Certificate

active

07026166

ABSTRACT:
The present invention relates to the use of fluorogenic or chromogenic dyes as reporter molecules for detecting cell entry by a specific molecule.

REFERENCES:
patent: 3728113 (1973-04-01), Becker et al.
patent: 3854945 (1974-12-01), Bush et al.
patent: 4713324 (1987-12-01), Fox et al.
patent: 4751286 (1988-06-01), Packard et al.
patent: 4868132 (1989-09-01), Byrnes et al.
patent: 4889916 (1989-12-01), Packard et al.
patent: 5055561 (1991-10-01), Packard et al.
patent: 5573773 (1996-11-01), Kis et al.
patent: 5573904 (1996-11-01), Mattingly
patent: 5756771 (1998-05-01), Mattingly
patent: 5800996 (1998-09-01), Lee et al.
patent: 5804604 (1998-09-01), Frank et al.
patent: 5986094 (1999-11-01), Ghoshal et al.
patent: 6221604 (2001-04-01), Upadhya et al.
patent: 6379965 (2002-04-01), Boutin
patent: 6756207 (2004-06-01), Giuliano et al.
patent: 2002/0151062 (2002-10-01), Zuckermann et al.
patent: 2003/0215798 (2003-11-01), Short et al.
patent: 199 35 302 (2001-02-01), None
patent: 0264797 (1996-01-01), None
patent: WO 79/00515 (1979-08-01), None
patent: WO 94/04686 (1994-03-01), None
patent: WO 98/52614 (1998-11-01), None
patent: WO 01/08707 (2001-02-01), None
Daugherty PS et al. Flow cytometric screening of cell-based libraries. J. Immunol. Methods 2000;243:211-227.
Huang CY et al. Lipitoids—novel cationic lipids for cellular delivery of plasmid DNA in vitro. Chemistry & Biology 1998;5:345-354.
Wender PA et al. The design, synthesis, and evaluation of molecules that enable or enhance cellular uptake: Peptoid molecular transporters. Proc. Natl. Acad. Sci. USA. 2000;97:13003-13008.
Murphy JE et al. A combinatorial approach to the discovery of efficient cationic peptoid reagents for gene delivery. Proc. Natl. Acad. Scid. USA. 1998;95:1517-1522.
Corrie, J.E.T. et al. A homobifunctional rhodamine for labeling proteins with defined orientations of a fluorophore. Bioconjugate Chem. 1998;9:160-167.
Forkey, J.N. et al. Protein structural dynamics by single-molecule fluorescence polarization (Review). Prog. Biophys. Mol. Biol. 2000;74:1-35.
Wingender, E. & Arellano, A. Synthesis and properties of the thiol-specific reagent difluorescein disulfide: its application on histon-histone and histone-DNA interactions. Anal. Biochem. 1982;127:351-360.
Graber et al., “Characteristics of Fluorprobes for Measuring Intracellular pH”, Analytical Biochemistry 156, 202-212 (1986).
Shipchandler et al., “4′-[Aminomethyl] fluorescein and Its N-Alkyl Derivatives: Useful Reagents in Immunodiagnostic Techniques”, Analytical Biochemistry 162, 89-101 (1987).
Rothbard et al., Conjugation of arginine oligomers to cyclosporin A facilitates topical delivery and inflammation, Nature Medicine, vol. 6, No. 11, Nov. 2000, pp. 1253-1257.
Dive et al., “Polar fluorescein derivatives as improved substrate probes for flow cytoenzymological assay of cellular esterases”, Molecular and Cellular Probes (1988) 2, 131-145.
Fawell et al., “Tat-mediated delivery of heterologous proteins into cells”, Proc. Natl. Acad. Sci USA, vol. 91, Jan. 1994, pp. 664-668.

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