Fluorocarbon contrast media for use with MRI and radiographic im

Details Fluorocarbon contrast media for use with MRI and radiographic im Fluorocarbon contrast media for use with MRI and radiographic im

1991-04-12

1996-03-05

Raymond, Richard L.

Drug, bio-affecting and body treating compositions

In vivo diagnosis or in vivo testing

Magnetic imaging agent

424 94, 424 44, 1286534, A61K 4904

Patent

active

054965357

ABSTRACT:
This invention relates to a non-aqueous fluorocarbon composition for use in magnetic resonance imaging (MRI) or radiographic imaging (X-ray or computed tomography), particularly imaging of the gastrointestinal (GI) tract. The invention also relates to an improved fluorocarbon composition with enhanced contrast effects in the GI tract. This invention further discloses an improved fluorocarbon composition having improved palatability. The invention further provides improved preparations for radiographic imaging or MRI. Methods for producing and using such preparations are disclosed, as are methods for improving the palatability of non-aqueous liquids. Finally, methods for improving imaging are disclosed.

REFERENCES:
patent: 3639568 (1972-02-01), Schmitt
patent: 3975512 (1976-08-01), Long
patent: 4074709 (1978-02-01), Kaplan
patent: 4120946 (1978-10-01), Queuille et al.
patent: 4215103 (1980-07-01), Millington
patent: 4927624 (1990-05-01), Bryant et al.
patent: 4971785 (1990-11-01), Wilson et al.
patent: 4994258 (1991-02-01), Burns
SMRI Brochure from 9th annual meeting, Apr. 13-17, 1991.
File Server Derwent, File WPI, Abstract no. 76-58263X, & JP,A, 50027399 (Miyata Ind KK) 20 Mar. 1975, see abstract.
File Server Derwent, File WPI, Abstract no. 71-01668s, & US, A, 3553127 (Ansul Co.) 5 Jan. 1971, see abstract.

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