Fluorocarbon compositions for pulmonary therapy

Details Fluorocarbon compositions for pulmonary therapy Fluorocarbon compositions for pulmonary therapy

1995-06-07

2000-12-26

Cook, Rebecca

Drug, bio-affecting and body treating compositions

Designated organic nonactive ingredient containing other...

Aftertreated solid synthetic organic polymer

514653, 514937, A61K 4700, A01N 2500

Patent

active

061660922

ABSTRACT:
Biocompatible fluorocarbon compositions are provided which may be used for the delivery of bioactive agents to the pulmonary air passages of a patient. Preferred compositions comprise a fluorocarbon liquid carrier having a bioactive agent in a solid or immiscible liquid form distributed therein. The disclosed compositions allow for the selective delivery of bioactive agents in conjunction with liquid lavage and liquid ventilation for the treatment of ARDS and other pulmonary disorders.

REFERENCES:
patent: 3737550 (1973-06-01), Nook et al.
patent: 3975512 (1976-08-01), Long
patent: 4233984 (1980-11-01), Walling
patent: 4252827 (1981-02-01), Yokoyamu et al.
patent: 4414209 (1983-11-01), Cook et al.
patent: 4669463 (1987-06-01), McConnell
patent: 4740103 (1988-04-01), Theeuwes
patent: 4881542 (1989-11-01), Schmidt et al.
patent: 4955375 (1990-09-01), Martinez
patent: 4976261 (1990-12-01), Gluck et al.
patent: 5011678 (1991-04-01), Wang et al.
patent: 5031613 (1991-07-01), Smith et al.
patent: 5043165 (1991-08-01), Radhakrishnam
Bogy, D.B. (1979) Drop formation in a circular liquid jet, Ann. Rev. Fluid. Mech. 11;207-228.
Bogy, D.B. (1979) Break-up of a liquid jet: third perturbation Cosserat solution. Phys. Fluids 22(2) :224-230.
Crane, L., et al. (1964) The effect of mechanical vibration on the break-up of a cylindrical water jet in air. Brit. J. Appl. Phys. 15:743-751.
Curry, S.A. and H. Portig (1977) Scale model of an ink jet. IBM J. Res. Devel., pp. 10-20.
Dabora, E.K. (1967) Production of monodisperse sprays. The Review of Scientific Instruments 38(4) :502-506.
Keeling, M.R. (1981) Ink Jet Printing, Phys. Technol. 12:196-203.
Levanoni, M. (1977) Study of fluid flow through scaled-up ink jet nozzles, IBM J. Res. Develop., pp. 56-68.
Marmor, J.B., et al. (1982) Clinical studies with ultrasound-induced hyperthermia, Stn. File Supplier & File Medline AN=83088921 (Karlsruhe) Natl. Cancer Inst. Monogr., vol. 61, pp. 333-337.
Sakai, T., and M. Hoshino (1980) Production of uniform droplets by longitudinal vibration of audio frequency. Journ. Chem. Engineering Japan 13 (4) :263-268.
Sekins, K.M. et al. (1988) Lung cancer hyperthermia via ultrasound and PFC liquids, 78-80, 5th International Symposium on Hyperthermic Oncology, Kyoto, Japan.
Sekins, K.M., et al. (1989) Intracavitary and external ultrasound byperthermia of the lung using PFC liquids. pp. 81-82, Ninth Annual Meeting of the North American Hyperthermia Group, Seattle, Washington.
Sekins, K.M., et al. (1989) Intracavity and external ultrasound hyperthermia of the lung Using PFC liquids, Abstract Ad-5, p. 9, Abstracts of Papers for the Thirty-Seventh Annual Meeting of the Radiation Research Society, Ninth Annual Meeting of the North American Hyperthermia Group, Seattle, Washington, Mar. 18-23, 1989.
Wissema, J.G. and G.A. Davies (1966) The formation of uniformly sized drops by vibration-atomization. The Canadian Journal of Chemical Engineering, 47:530-535.
Wolfson, M.R. and T.H. Shaffer (1990) Pulmonary administration of drugs (PAD) : A new approach for drug delivery using liquid ventilation. FASEB Journal 4 (4) :A11005.
CA103:115853, Hild et al, 1985.
Skibba et al, abstract, Eur. Sug. Res., 17(5), 301-9, 1985.

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