Fluorobenzamides and uses thereof

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Ester doai

Reexamination Certificate

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Details

C514S616000, C514S622000, C558S392000, C558S415000, C564S155000, C564S171000

Reexamination Certificate

active

06951884

ABSTRACT:
The invention relates to fluorobenzamide derivatives of the formulawherein R1, R2, R3R4, R5, R6and R7are as defined herein. =,The compounds of the invention are selective monoamine oxidase B inhibitors and therefore they are suitable for the treatment of diseases mediated by monoamine oxidase B, such as Alzheimer's disease or senile dementia.

REFERENCES:
patent: 4906626 (1990-03-01), Amrein et al.
patent: 5889026 (1999-03-01), Alanine et al.
patent: 0 326 023 (1989-08-01), None
Bach et al., Proc. Natl. Acad. Sci. USA, 85 pp. 4934-4938 (1988).
Cesura et al., Prog. Drug Research, 38, 171-297 (1992).
Fowler et al., J. Neural. Tranm., 49, pp. 1-20 (1980).
Benedetti et al., Biochem. Pharmacol., 38, pp. 555-561 (1989).
Saura et al., Neuroscience, 70, 755-774 (1996).
Bentué-Ferrer et al., CNS Drugs, 6, pp. 217-236 (1996).
Zhou et al., Analytical Biochemistry, 253, pp. 169-174 (1997).

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