Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Ester doai
Reexamination Certificate
2005-10-04
2005-10-04
Richter, Johann (Department: 1626)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Ester doai
C514S616000, C514S622000, C558S392000, C558S415000, C564S155000, C564S171000
Reexamination Certificate
active
06951884
ABSTRACT:
The invention relates to fluorobenzamide derivatives of the formulawherein R1, R2, R3R4, R5, R6and R7are as defined herein. =,The compounds of the invention are selective monoamine oxidase B inhibitors and therefore they are suitable for the treatment of diseases mediated by monoamine oxidase B, such as Alzheimer's disease or senile dementia.
REFERENCES:
patent: 4906626 (1990-03-01), Amrein et al.
patent: 5889026 (1999-03-01), Alanine et al.
patent: 0 326 023 (1989-08-01), None
Bach et al., Proc. Natl. Acad. Sci. USA, 85 pp. 4934-4938 (1988).
Cesura et al., Prog. Drug Research, 38, 171-297 (1992).
Fowler et al., J. Neural. Tranm., 49, pp. 1-20 (1980).
Benedetti et al., Biochem. Pharmacol., 38, pp. 555-561 (1989).
Saura et al., Neuroscience, 70, 755-774 (1996).
Bentué-Ferrer et al., CNS Drugs, 6, pp. 217-236 (1996).
Zhou et al., Analytical Biochemistry, 253, pp. 169-174 (1997).
Jolidon Synese
Rodriguez Sarmiento Rosa Maria
Thomas Andrew William
Wyler Rene
Prior Kimberly J.
Richter Johann
Rocha-Tramaloni Patricia S.
Sackey Ebenezer
LandOfFree
Fluorobenzamides and uses thereof does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Fluorobenzamides and uses thereof, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Fluorobenzamides and uses thereof will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3458379