Fluoroalkylated amphiphilic ligands, their metallic complexes an

Details Fluoroalkylated amphiphilic ligands, their metallic complexes an Fluoroalkylated amphiphilic ligands, their metallic complexes an

1995-01-25

1997-07-15

Reamer, James H.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

546 88, A61K 31435

Patent

active

056483627

ABSTRACT:
Fluoroalkylated amphiphilic ligands are derived from aromatic amines of the bipyridine (I) or phenanthroline (II) types, and form complexes with platinum, palladium and ruthenium. ##STR1## In formulae (I) and (II), R.sup.1 and R.sup.2 are independently a hydrogen atom, or a fluoroalkylated or hydrocarbon chain, provided at least one of R.sup.1 and R.sup.2 is a fluoroalkylated chain, and W represents a methylene, ester, ether, carbonyl or amide group.
Fluoroalkylated ligands (I or II) and their complexes can be included in preparations comprising emulsions, dispersions, gels, or microemulsions, particularly in preparations for therapeutic use.

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