Fluorine-containing hydrogel-forming polymeric materials

Synthetic resins or natural rubbers -- part of the class 520 ser – Synthetic resins – Mixing of two or more solid polymers; mixing of solid...

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351160R, 351160H, 523106, 523107, 523108, 525117, 525118, 525119, 525121, 525293, 525301, 525302, 526245, 526264, C08F21418, G02C 704

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active

044331118

ABSTRACT:
Polymeric materials suitable for biomedical applications, particularly in making contact lenses, are formed by copolymerization and crosslinking of: (1) an amide of an unsaturated carboxylic acid such as acrylamide or methacrylamide; (2) an N-vinyl lactam such as N-vinyl pyrrolidone; (3) an ester of an unsaturated carboxylic acid such as a hydroxy-substituted ester of acrylic or methacrylic acid; (4) an unsaturated carboxylic acid such as acrylic or methacrylic acid; and (5) a hydrophobic monomer component comprising: (a) a fluorine-containing polymerizable monomer having a fluoroaliphatic side chain, such as fluoroalkyl acrylate or methacrylate, and (b) a non-fluorine-containing polymerizable hydrophobic vinyl monomer such as styrene; crosslinking with a crosslinking agent either being carried out during copolymerization or subsequently. The resulting polymeric materials may be machined to produce a contact lens form and then hydrated to form a hydrogel which is suitable for use as an extended wear contact lens.

REFERENCES:
patent: 3658857 (1972-04-01), Kleiner et al.

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