Fluorinated triethylenediamine as an oxygen transport agent

Organic compounds -- part of the class 532-570 series – Organic compounds – Nitrogen attached directly or indirectly to the purine ring...

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514249, C07D48708, A61K 31495, C07B 3900

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active

048144460

ABSTRACT:
Fluorinated triethylenediamine compounds such as perfluorotriethylenediamine and the novel compounds undecafluorotriethylenediamine and decafluorotriethylenediamine, prepared by indirect fluorination of triethylenediamine by passing triethylenediamine over, e.g., cobalt trifluoride (CoF.sub.3), is useful as a material capable of carrying oxygen in an aqueous emulsion for lifesaving a patient suffering from massive hemorrhage and for preserving internal organs in transplantation. The compounds undergo rapid biological elimination due to their low molecular weight.

REFERENCES:
patent: 3335143 (1967-08-01), Erner
Remington's Pharme Central Sciences, 15th Edition, pp. 656-659, 248-249, 612-637.
All Tech. Associates' Bulletin #87 (1986).

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