Fluorinated polyenes

Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal

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2603478, 2603474, 260408, 260599, 260600R, 568649, 568654, 568812, 568663, 560 60, 560105, 424275, 424285, 424308, 424315, 424324, 424333, 424343, 549 77, 549 78, 549 79, C09F 500, C11C 300, A01N 924

Patent

active

041713184

ABSTRACT:
9-Substituted, 4- or 6-fluorine substituted retinoic acid derivatives useful as antitumor agents and in the treatment of acne as well as a method for their manufacture are disclosed. Substituents at the 9-position include substituted phenyl, thienyl and furyl groups.

REFERENCES:
patent: 3883508 (1975-05-01), Cook
patent: 4054589 (1977-10-01), Bollag et al.
patent: 4061656 (1977-12-01), Klaus et al.

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