Organic compounds -- part of the class 532-570 series – Organic compounds – Carboxylic acid esters
Patent
1981-08-21
1984-03-27
Shippen, Michael L.
Organic compounds -- part of the class 532-570 series
Organic compounds
Carboxylic acid esters
2601125R, 560 39, 560 41, 562448, 562449, 562561, 562565, 564157, 564159, 564164, 564182, 564187, 564197, 564198, 564215, 564509, 424177, 424314, 424319, 424325, C07C10124, C07C 8726
Patent
active
044396198
ABSTRACT:
Fluorinated alkenylene diamine compounds are inhibitors of ornithine decarboxylase enzyme in vivo and have the following formula: ##STR1## wherein: R.sub.a represents hydrogen or R.sub.2, where R.sub.2 is as defined below;
REFERENCES:
patent: 2662915 (1953-12-01), Lontz
patent: 4323704 (1982-04-01), Metcalf
patent: 4325961 (1982-04-01), Kollonitsch
patent: 4326071 (1982-04-01), Bey
Mamont, Biochem. Biophys. Res. Comm., 81, p. 58, (1978).
Metcalf, J. Am. Chem. Soc., 100, p. 255, (1978).
Kollonitsch, Nature, 274, p. 906, (1978).
Bey Philippe
Gerhart Fritz
Jung Michel
McDonald Raymond A.
Merrell Toraude et Compagnie
Shippen Michael L.
Street Gary D.
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