Fluorinated nitro- and aminoalcohols

Details Fluorinated nitro- and aminoalcohols Fluorinated nitro- and aminoalcohols

1986-11-06

1988-10-18

Raymond, Richard L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Oxygen containing

568713, 549445, C07C 7918, C07C 7920, C07C 7922

Patent

active

047789352

ABSTRACT:
Fluorinated nitroalcohols of the formula (I) ##STR1## process for their preparation by reaction of fluoronitroalkane of the formula (II) ##STR2## with a carbonyl compound of the formula (III) ##STR3## fluorinated aminoalcohols of the formula (IV) ##STR4## and a process for their preparation by hydrogentation of compounds of the formula (I).

REFERENCES:
Seeback, D. et al., Angewandte Chemie, vol. 25, No. 1, pp. 98-99 (1986).
Knunyants, I. L. et al., Chemical Abstracts vol. 62, No. 430c, (1965).
Angewandte Chemie, Band 98, Nr. 1, Jan. 1986, Seiten 96-97, VCH Verlagsgesellschaft mbH, Weinheim, DE; D. Seebach et al.: "Diund Trifluorosubstituierte Dilithium-Verbindungen fur die Organische Synthese" *Seite 97; Verbindungen 6-9*.
Journal of Pharmaceutical Sciences, Band 56, Nr. 8, Aug. 1967, Seiten 970-973, American Pharmaceutical Association, Washington, D.C. US; R. M. Pinder et al.: "Trifluoromethyl Analogs of Amphetamine and Norephedrine" *Seite 972, Rechte Spalte, Abschnitt 6*.

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