Fluorinated ketones and method for making same

Organic compounds -- part of the class 532-570 series – Organic compounds – Oxygen containing

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568403, 568407, C07C 4580

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active

059986719

ABSTRACT:
A method for the preparation of a fluorinated ketone of the formula: ##STR1## where R.sub.1 and R.sub.2 are independently fluorine, alkyl of from about 1 to about 8 carbon atoms, fluoroalkyl of from about 1 to about 8 carbon atoms, or ##STR2## where R.sub.3 and R.sub.4 are independently fluorine, alkyl of from about 1 to about 8 carbon atoms, or fluoroalkyl of from about 1 to about 8 carbon atoms and n is 0 or 1. The method includes heating an anhydride of the formula: ##STR3## with a catalyst including a cationic salt of a fluorocarboxylic acid or an alkali metal fluoride to obtain the fluorinated ketone.

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"Trifluoroacetic Acid: Sources Of Trifluoromethyl Groups Access To Derivatives Of Triflic Acid", J. R. Desmers, G. Forat, J.M. Mas, V. Pevere, S. Ratton, N. Roques, J. Russell, L. Saint-Jalmes, Abstract O(3) C-5, 15th International Symposium of Fluorine Chemistry, Vancouver, Canada, Aug. 1997.
"Formation of Symmetrical Ketones From Self-Condensations of Anhydrides by Boron Fluoride", E. H. Man and C. R. Hauser, J. Am. Chem. Soc., 72, (1950), 3294.

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