Fluorinated derivatives of mevinic acids

Details Fluorinated derivatives of mevinic acids Fluorinated derivatives of mevinic acids

1990-05-11

1992-02-18

Rotman, Alan L.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514510, 549292, 560119, A61K 31365, C07D30930

Patent

active

050895230

ABSTRACT:
Compounds of the formula ##STR1## and pharmaceutically acceptable salts and tautomeric mixtures thereof possess activity as HMg-CoA reductase inhibitors, thus making them useful as antihypercholesterolemic agents. In the above formula,

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patent: 4719229 (1988-01-01), Reamer et al.
F. M. Singer et al., Proc. Soc. Exper. Biol. Med., 102, 370-372, (1959).

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