Fluorinated aromatic polyenes

Details Fluorinated aromatic polyenes Fluorinated aromatic polyenes

1979-11-21

1981-05-05

Niebling, John F.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acid esters

562465, 568442, 568592, 568649, 424308, 424317, 424333, 424341, C07C 6976, C07C 5900

Patent

active

042660734

ABSTRACT:
Compounds representd by the formula ##STR1## wherein R.sub.1, R.sub.2 and R.sub.3 are lower alkyl, R.sub.4 is lower alkoxy, R.sub.6 and R.sub.8 are methyl or trifluoro methyl, R.sub.9 is formyl, hydroxymethyl, alkoxymethyl, alkanoyloxymethyl, carboxyl, alkoxycarbonyl, lower alkenoxycarbonyl, lower alkynoxycarbonyl, carbamoyl, mono(lower alkyl)-carbamoyl, di(lower alkyl)carbamoyl or N-heterocyclylcarbonyl, R.sub.5, R.sub.7, R.sub.10, R.sub.11, R.sub.12 and R.sub.13 are hydrogen or fluorine with the proviso that at least one of R.sub.5, R.sub.7, R.sub.10, R.sub.11, R.sub.12 or R.sub.13 is fluorine or at least one of R.sub.6 or R.sub.8 is trifluoro methyl, or pharmaceutically acceptable salts thereof useful as antitumor agents are disclosed.

REFERENCES:
patent: 3163669 (1964-12-01), Stilz
patent: 3657306 (1972-04-01), Murray
patent: 3862969 (1975-01-01), Henrick
patent: 3954817 (1976-05-01), Jager
Ike, T. et al., Bull. Chem. Soc. Jap., (1974), vol. 47, pp. 350-354.

Affiliated with

Also associated with

Rating

Fluorinated aromatic polyenes does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Fluorinated aromatic polyenes, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Fluorinated aromatic polyenes will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-296802