Fluorimetric immunoassay for diphenylhydantoin

Drug – bio-affecting and body treating compositions – Radionuclide or intended radionuclide containing; adjuvant... – Molecular bilayer structure

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Details

23230B, 424 12, G01N 3316, G01N 2152

Patent

active

041608186

ABSTRACT:
Substituted hydantoin drugs (for example phenytoin) and tricyclic antidepressant drugs (for example nortriptyline) are assayed by mixing them with a fluorescent labelled compound and antibodies, and measuring the fluorescence of the mixture. The assay does not necessitate any separation step and may be effected by continuous-flow techniques.

REFERENCES:
patent: 2797149 (1957-06-01), Skeggs
patent: 3901654 (1975-08-01), Gross
patent: 3995021 (1976-11-01), Gross
patent: 3996345 (1976-12-01), Ullman
patent: 3998943 (1976-12-01), Ullman
patent: 4036946 (1977-07-01), Kleinerman

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